Exposure to di-n-octyl phthalate during puberty induces hypergonadotropic hypogonadism caused by Leydig cell hyperplasia but reduced steroidogenic function in male rats.
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DOI: 10.1016/j.ecoenv.2020.111432
Abstract: Humans are exposed to phthalates ubiquitously, which may threaten health. However, whether di-n-octyl phthalate can prevent pubertal sexual maturity is still elusive. In this study, male Sprague Dawley rats (age 35 days) were treated daily… read more here.
Keywords: leydig cell; phthalate; octyl phthalate; cell hyperplasia ... See more keywords