Relapse in patients with limited‐stage ocular adnexal lymphoma treated by chemoimmunotherapy: Extended follow‐up of a phase 2 study
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DOI: 10.1002/cam4.4639
Abstract: Approximately 50% of limited‐stage ocular adnexal mucosa‐associated lymphoid tissue lymphoma (OAML) patients with adverse prognostic factors relapse after radiotherapy. Chemoimmunotherapy has been proposed as an alternative frontline therapy. However, only a few studies have reported… read more here.
Keywords: lymphoma; limited stage; ocular adnexal; stage ocular ... See more keywords
Second primary malignancies of eye and ocular adnexa after a first primary elsewhere in the body
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DOI: 10.1007/s00417-020-04896-1
Abstract: Purpose The eye and its adnexal structures can give rise to first or consecutive primary malignancies or to encounter metastasis. Our aim was to define the characteristics of the second primary neoplasms affecting the eye… read more here.
Keywords: second primary; malignancies eye; primary malignancies; ocular adnexal ... See more keywords
Effects of mitomycin-C and 5-fluorouracil on ocular adnexal sebaceous carcinoma cells.
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DOI: 10.1016/j.ajo.2021.12.016
Abstract: PURPOSE To investigate the effects of mitomycin-C (MMC) and 5-fluorouracil (5-FU) on the viability, proliferation, and migratory capacity of cultured ocular adnexal sebaceous carcinoma (SC) cells. DESIGN Laboratory investigation. METHODS Human SC cell lines (Bascom… read more here.
Keywords: sebaceous carcinoma; viability; adnexal sebaceous; effects mitomycin ... See more keywords
Whole-exome sequencing for ocular adnexal sebaceous carcinoma suggests PCDH15 as a novel mutation associated with metastasis
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DOI: 10.1038/s41379-020-0454-y
Abstract: Ocular adnexal sebaceous carcinoma (OASeC) is an aggressive eyelid carcinoma. Analysis of molecular-genetic drivers of this disease could reveal new prognostic markers and actionable targets for treatment. To identify somatically acquired genomic mutations in OASeC… read more here.
Keywords: carcinoma; associated metastasis; metastasis; ocular adnexal ... See more keywords
Clinical analysis of ocular adnexal mucosa-associated lymphoid tissue lymphoma with IgG4-related ophthalmic disease.
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DOI: 10.1080/01676830.2021.1962365
Abstract: PURPOSE To analyse the incidence and characteristics of ocular adnexal mucosa-associated lymphoid tissue lymphoma (OAML) with immunoglobulin G4 (IgG4)-related ophthalmic disease (IgG4-ROD), and to compare with IgG4-negative OAML. METHODS We enrolled 130 patients with pathology-confirmed… read more here.
Keywords: igg4; igg4 rod; disease; igg4 positive ... See more keywords
Clinical characteristics and outcomes of ocular adnexal mantle cell lymphoma
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DOI: 10.1080/01676830.2021.2018715
Abstract: ABSTRACT Purpose To compare characteristics of initial ocular adnexal (OA) mantle cell lymphoma (MCL) and initial systemic MCL. Methods Retrospective, comparative case series. Patients treated for MCL at Mayo Clinic from 1/1/1990 to 11/30/2020. MCL… read more here.
Keywords: cell; adnexal mantle; initial systemic; ocular adnexal ... See more keywords
Usefulness of 18F-FDG PET/CT for evaluating response of ocular adnexal lymphoma to treatment
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DOI: 10.1097/md.0000000000010543
Abstract: Abstract The purpose of this study was to investigate the efficacy of 18F-fluoro-deoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) for evaluating the ocular adnexal lymphoma treatment responses. We retrospectively reviewed data for 9 histologically confirmed… read more here.
Keywords: lymphoma; lymphoma treatment; ocular adnexal; adnexal lymphoma ... See more keywords
Rare case of ocular adnexal relapse with mantle cell lymphoma treated with ibrutinib monotherapy
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DOI: 10.1111/imj.14432
Abstract: November and February, the exhilarating day could start at 5 am with a public announcement for whale and orca pod sighting to a midnight return after long hikes on unsteady, rugged and deeply snowed terrain… read more here.
Keywords: adnexal relapse; rare case; case ocular; relapse mantle ... See more keywords
Prevalence and prognostic value of MYD88 and CD79B mutations in ocular adnexal large B-cell lymphoma: a reclassification of ocular adnexal large B-cell lymphoma
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DOI: 10.1136/bjophthalmol-2021-319580
Abstract: Aims To (1) reclassify ocular adnexal large B-cell lymphomas (OA-LBCLs) per 2016 WHO lymphoma classification and (2) determine the prevalence of MYD88 and CD79B mutations and their association with clinical parameters among OA-LBCLs. Methods This… read more here.
Keywords: adnexal large; large cell; ocular adnexal; cell ... See more keywords
Paediatric ocular adnexal lymphoma: a population-based analysis
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DOI: 10.1136/bmjophth-2020-000483
Abstract: Objective To investigate the incidence, clinicopathological characteristics and survival of ocular adnexal lymphoma (OAL) in the paediatric population. Methods and analysis In this retrospective case series, the Surveillance, Epidemiology and End Results database was accessed… read more here.
Keywords: lymphoma; oal; ocular adnexal; adnexal lymphoma ... See more keywords
Distinct Biological Types of Ocular Adnexal Sebaceous Carcinoma: HPV-Driven and Virus-Negative Tumors Arise through Nonoverlapping Molecular-Genetic Alterations
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DOI: 10.1158/1078-0432.ccr-18-1688
Abstract: Purpose: Ocular adnexal (OA) sebaceous carcinoma is an aggressive malignancy of the eyelid and ocular adnexa that frequently recurs and metastasizes, and effective therapies beyond surgical excision are lacking. There remains a critical need to… read more here.
Keywords: sebaceous carcinoma; tumors arise; molecular genetic; ocular adnexal ... See more keywords