Risk of Ocular Adverse Events Associated With Use of Phosphodiesterase 5 Inhibitors in Men in the US.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2022.0663
Abstract: Importance A number of case reports and small epidemiologic studies have quantified the risk of ocular adverse events associated with the use of phosphodiesterase type 5 inhibitors (PDE5Is). However, results have been conflicting, and epidemiologic… read more here.
Keywords: srd rvo; ocular adverse; risk; rvo ion ... See more keywords
Advancing Ocular Safety Profile Assessment: A Novel Grading Scale for Ocular Adverse Reactions Associated with Bemarituzumab
Sign Up to like & getrecommendations! Published in 2025 at "Ophthalmology and Therapy"
DOI: 10.1007/s40123-025-01139-6
Abstract: Targeted cancer therapies have transformed the landscape of cancer treatments but are often associated with off-target adverse drug reactions due to overlapping molecular pathways in healthy tissues, including those in the eye. Fibroblast growth factor… read more here.
Keywords: ocular adverse; adverse reactions; grading scale; safety profile ... See more keywords
Ocular adverse events with immune checkpoint inhibitors
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Current Ophthalmology"
DOI: 10.1016/j.joco.2019.05.002
Abstract: Purpose To quantify the risk of ocular adverse events with immune checkpoint inhibitors (ICIs) as reported to the Food and Drug Administration (FDA). Methods Disproportionality analysis using data from U.S. FDA's Adverse Events Reporting System… read more here.
Keywords: immune checkpoint; checkpoint inhibitors; ocular adverse; adverse events ... See more keywords
Association of ocular adverse events with varenicline solution use: a population-based study
Sign Up to like & getrecommendations! Published in 2025 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2025.2460454
Abstract: ABSTRACT Background Approved by the FDA in 2021, varenicline solution is the first nasal spray specifically designed to enhance basal tear film production for treating dry eye disease (DED). However, there is a lack of… read more here.
Keywords: ocular adverse; adverse events; use; varenicline solution ... See more keywords
Ocular adverse effects of bladder medication: a systematic review
Sign Up to like & getrecommendations! Published in 2022 at "Cutaneous and Ocular Toxicology"
DOI: 10.1080/15569527.2022.2052889
Abstract: Abstract Background With the ageing population, lower urinary tract symptoms are becoming more prevalent with an estimate that by 2025, 52 million adults in the USA will be affected. After lifestyle modifications fail to resolve… read more here.
Keywords: medication; review; bladder medication; ocular adverse ... See more keywords
OCULAR ADVERSE EVENTS ASSOCIATED WITH MEK INHIBITORS.
Sign Up to like & getrecommendations! Published in 2019 at "Retina"
DOI: 10.1097/iae.0000000000002451
Abstract: PURPOSE Mitogen-activates protein kinase (MAPK) inhibitors, particularly MEK inhibitors, have shifted the treatment paradigm for metastatic BRAF-mutant cutaneous melanoma; however, oncologists, ophthalmologists, and patients have noticed different toxicities of variable importance. This review aims to… read more here.
Keywords: mek inhibitors; ocular adverse; events associated; adverse events ... See more keywords
Ocular toxicities associated with antibody drug conjugates
Sign Up to like & getrecommendations! Published in 2024 at "Current Opinion in Ophthalmology"
DOI: 10.1097/icu.0000000000001063
Abstract: Purpose of review To review the structure, mechanism of action, and pathophysiology of antibody-drug conjugates (ADCs) used to treat gynecological malignancies associated with ocular adverse effects. Recent findings Recent research shows tisotumab vedotin causes ocular… read more here.
Keywords: ocular adverse; ocular toxicities; adverse effects; antibody drug ... See more keywords
Ocular adverse events in patients with atopic dermatitis undergoing treatment with dupilumab: An Italian single‐center experience
Sign Up to like & getrecommendations! Published in 2021 at "Dermatologic Therapy"
DOI: 10.1111/dth.15059
Abstract: Ocular comorbidities are more frequent in patients with severe atopic dermatitis (AD) compared to general population. Dupilumab, a fully human monoclonal antibody that prevents the signaling of interleukin (IL)‐4 and IL‐13, is reported to be… read more here.
Keywords: events patients; treatment; atopic dermatitis; ocular adverse ... See more keywords
Difference in the rate of ocular adverse events with dupilumab between asthma and atopic dermatitis patients
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Dermatology"
DOI: 10.1111/ijd.15524
Abstract: dupilumab between asthma and atopic dermatitis patients Dear Editor, Dupilumab is a monoclonal antibody that inhibits the signaling of both IL-4 and IL-13, which are involved in many allergic disorders. Dupilumab is currently approved by… read more here.
Keywords: patients treated; atopic dermatitis; ocular adverse; adverse events ... See more keywords
Bisphosphonate-related ocular adverse events: a pharmacovigilance study based on the FAERS database.
Sign Up to like & getrecommendations! Published in 2025 at "Endocrine connections"
DOI: 10.1530/ec-25-0482
Abstract: This retrospective study aimed to identify and characterize signals of ocular adverse events (AEs) related to bisphosphonates (BPs) using FDA adverse event reporting system (FAERS) data (Q1 2004 to Q3 2024) to inform future safety… read more here.
Keywords: ocular adverse; alendronate zoledronate; adverse events; related ocular ... See more keywords
The ocular adverse effects of oral drugs
Sign Up to like & getrecommendations! Published in 2021 at "Australian Prescriber"
DOI: 10.18773/austprescr.2021.028
Abstract: SUMMARY Some commonly prescribed drugs have ocular adverse effects. Many parts of the eye can be affected by oral drugs. Some ocular adverse effects may be reversed with medical or surgical intervention whereas other drugs… read more here.
Keywords: drugs ocular; oral drugs; ocular adverse; effects oral ... See more keywords