Oxidative stress and mitochondrial transfer: A new dimension towards ocular diseases
Sign Up to like & getrecommendations! Published in 2020 at "Genes and Diseases"
DOI: 10.1016/j.gendis.2020.11.020
Abstract: Abstract Ocular cells like, retinal pigment epithelium (RPE) is a highly specialized pigmented monolayer of post-mitotic cells, which is located in the posterior segment of the eye between neuro sensory retina and vascular choroid. It… read more here.
Keywords: mitochondrial transfer; diseases oxidative; ocular diseases; stress ... See more keywords
Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.8b00971
Abstract: Ocular diseases featuring pathologic neovascularization are the leading cause of blindness, and anti-VEGF agents have been conventionally used to treat these diseases. Recently, regulating factors upstream of VEGF, such as HIF-1α, have emerged as a… read more here.
Keywords: ocular diseases; novel scaffold; hypoxia; factor ... See more keywords
Nano-based ocular drug delivery systems: an insight into the preclinical/clinical studies and their potential in the treatment of posterior ocular diseases.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d3bm00505d
Abstract: Numerous novel nano-based ocular drug delivery systems have been developed to overcome the limitations of conventional drug delivery systems, which have demonstrated promising results in ocular disease models and clinical practice. Of all the nano-based… read more here.
Keywords: delivery systems; nano based; drug delivery; ocular diseases ... See more keywords
Colombian Ocular Diseases Epidemiology Study (CODES): incidence and sociodemographic characterisation of keratoconus between 2015 and 2020
Sign Up to like & getrecommendations! Published in 2023 at "BMJ Open Ophthalmology"
DOI: 10.1136/bmjophth-2023-001238
Abstract: Objective To estimate the incidence and describe the demographic characteristics of keratoconus (KC) in Colombia using national health registry data between January 1st 2015 and December 31th 2020. Methods and analysis We conducted a nationwide,… read more here.
Keywords: incidence; colombian ocular; epidemiology; ocular diseases ... See more keywords
Involvement of Nrf2 in Ocular Diseases
Sign Up to like & getrecommendations! Published in 2017 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2017/1703810
Abstract: The human body harbors within it an intricate and delicate balance between oxidants and antioxidants. Any disruption in this checks-and-balances system can lead to harmful consequences in various organs and tissues, such as the eye.… read more here.
Keywords: involvement nrf2; ocular diseases; medicine; nrf2 ocular ... See more keywords
Epidemiology and clinical presentation of feline presumed hereditary or breed-related ocular diseases in France: retrospective study of 129 cats
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Feline Medicine and Surgery"
DOI: 10.1177/1098612x221080598
Abstract: Objectives This study aimed to describe the epidemiology and clinical presentation of presumed hereditary or presumed breed-related ocular diseases in a population of cats in France. Methods Medical records from between September 2013 and August… read more here.
Keywords: breed; presumed hereditary; related ocular; ocular diseases ... See more keywords
Systemic and ocular diseases associated with the development of diabetic macular edema among Japanese patients with diabetes mellitus
Sign Up to like & getrecommendations! Published in 2020 at "BMC Ophthalmology"
DOI: 10.1186/s12886-020-01578-8
Abstract: Background Diabetic macular edema (DME) causes severe vision loss among patients with diabetes mellitus (DM). We aimed to investigate systemic and ocular diseases associated with the development of DME in a Japanese population. Methods A… read more here.
Keywords: systemic ocular; diabetic macular; diseases associated; ocular diseases ... See more keywords
Possible therapeutic effect of magnesium in ocular diseases
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Basic and Clinical Physiology and Pharmacology"
DOI: 10.1515/jbcpp-2019-0107
Abstract: Abstract Magnesium (Mg2+) is one of the major elements required to maintain normal metabolism and ionic balances in ocular tissues. The physiological role of Mg2+ is mediated through maintaining the Na+-K+-ATPase on membrane, favoring energy-generating… read more here.
Keywords: therapeutic effect; effect magnesium; ocular diseases; mg2 ... See more keywords
Potential applications of artemisinins in ocular diseases.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2019.11.20
Abstract: Artemisinin, also named qinghaosu, is a family of sesquiterpene trioxane lactone originally derived from the sweet wormwood plant (Artemisia annua), which is a traditional Chinese herb that has been universally used as anti-malarial agents for… read more here.
Keywords: ophthalmology; ocular diseases; potential applications; artemisinins ocular ... See more keywords
Metabolomics and biomarkers in ocular matrix: beyond ocular diseases.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2020.06.21
Abstract: According to the recent report, there are 870 million people suffer from ocular diseases worldwide. The present approaches for diagnosis are morphological examination, imaging examination and immunological examination, regrettably, they lack of sensitivity and difficult… read more here.
Keywords: biomarkers ocular; metabolomics biomarkers; matrix beyond; ocular matrix ... See more keywords
Research progress of exosomes in pathogenesis, diagnosis, and treatment of ocular diseases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1100310
Abstract: Exosomes are natural extracellular vesicles with a diameter of 30–150 nm, which exist in biological fluids and contain biomolecules related to the parent cell, such as proteins, nucleic acids, lipids, etc. It has a wide… read more here.
Keywords: diagnosis; progress exosomes; pathogenesis diagnosis; ocular diseases ... See more keywords