Evidence for ceramide induced cytotoxicity in retinal ganglion cells.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental eye research"
DOI: 10.1016/j.exer.2021.108762
Abstract: Ceramides are bioactive compounds that play important roles in regulating cellular responses to extracellular stimuli and stress. Previous studies have shown that ceramides contribute to retinal degeneration associated with ischemic and ocular hypertensive stress. Acid… read more here.
Keywords: ocular hypertensive; retinal ganglion; ganglion cells; evidence ... See more keywords
Effect of acute intraocular pressure elevation on the minimum rim width in normal, ocular hypertensive and glaucoma eyes
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Ophthalmology"
DOI: 10.1136/bjophthalmol-2017-310232
Abstract: Background To estimate and compare changes in the Bruch’s membrane opening—minimum rim width (BMO–MRW) and area in normal, ocular hypertensive and glaucoma eyes following acute elevations in intraocular pressure (IOP). Methods The optic nerve heads… read more here.
Keywords: rim width; minimum rim; ocular hypertensive; glaucoma ... See more keywords
Reduction of Neuroinflammation by δ-Opioids Via STAT3-Dependent Pathway in Chronic Glaucoma Model
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.601404
Abstract: The main objective of this study was to determine the inhibition of pro-inflammatory cytokines and their associated signaling molecules by δ-opioid receptor activation by a selective ligand, SNC-121 in chronic rat glaucoma model. Intraocular pressure… read more here.
Keywords: snc 121; ocular hypertensive; hypertensive animals; glaucoma model ... See more keywords