Tacrolimus Loaded PEG-Cholecalciferol Based Micelles for Treatment of Ocular Inflammation
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DOI: 10.1007/s11095-018-2376-7
Abstract: PurposePoor corneal permeability, nasolacrimal drainage and requirement of chronic administration are major drawbacks of existing therapies for ocular inflammation. Hence, we designed topical micelles of PEG2000 conjugated with cholecalciferol (PEGCCF).MethodsIntegrin targeted tacrolimus loaded PEGCCF micelles… read more here.
Keywords: tacrolimus loaded; loaded peg; ocular inflammation; inflammation ... See more keywords
Down regulation of inflammatory cytokines by the bioactive resveratrol-loaded chitoniosomes in induced ocular inflammation model
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2021.102787
Abstract: Abstract Resveratrol (RSV); a natural polyphenol possess anti-inflammatory property through reduction of proinflammatory cytokines tumor-necrosis factor-alpha (TNFα) and interleukin (IL)-6 which play a key role in eye inflammation. Ocular inflammation results in irreversible tissues damage… read more here.
Keywords: ocular inflammation; inflammatory cytokines; bioactive resveratrol; regulation inflammatory ... See more keywords
The Role of Screening for Asymptomatic Ocular Inflammation in Sarcoidosis.
Sign Up to like & getrecommendations! Published in 2021 at "Ocular immunology and inflammation"
DOI: 10.1080/09273948.2021.1976216
Abstract: PURPOSE To determine the utility of routine screening ophthalmic exam in patients with systemic sarcoidosis and no history of uveitis. METHODS Prospective, single-center, observational study conducted at Northwestern University from October 11, 2012 to October… read more here.
Keywords: ocular inflammation; role screening; inflammation; screening asymptomatic ... See more keywords
Lipocalin 2 Suppresses Ocular Inflammation by Inhibiting the Activation of NF-κβ Pathway in Endotoxin-Induced Uveitis
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000488472
Abstract: Background/Aims: Lipocalin 2 (LCN2), an important mediator of a variety of cellular processes, is involved in regulating the inflammatory response, but its roles in different inflammatory diseases are controversial. Because the role of LCN2 in… read more here.
Keywords: lcn2; ocular inflammation; inflammation; ller cells ... See more keywords
[New possibilities in therapy of ocular inflammation in rheumatic diseases].
Sign Up to like & getrecommendations! Published in 2022 at "Vestnik oftalmologii"
DOI: 10.17116/oftalma2022138061108
Abstract: This review is devoted to the potential application of genetically engineered biological drugs of different classes in the treatment of main forms of uveitis and other types of non-infectious ocular inflammation in immunoinflammatory rheumatic diseases.… read more here.
Keywords: rheumatic diseases; inflammation; new possibilities; ocular inflammation ... See more keywords
Anti-inflammatory Effects of GTE in Eye Diseases
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2021.753955
Abstract: Ocular inflammation is a common complication of various eye diseases with wide consequences from irritations to potentially sight-threatening complications. Green tea is a popular beverage throughout the world. One of the proven health benefits of… read more here.
Keywords: green tea; ocular inflammation; eye diseases; inflammation ... See more keywords
A Pilot Study of a Panel of Ocular Inflammation Biomarkers in Patients with Primary Sjögren’s Syndrome
Sign Up to like & getrecommendations! Published in 2023 at "Current Issues in Molecular Biology"
DOI: 10.3390/cimb45040188
Abstract: Ocular diseases have a strong impact on individuals, the effects of which extend from milder visual impairment to blindness. Due to this and to their prevalence, these conditions constitute important health, social and economic challenges.… read more here.
Keywords: gren syndrome; study panel; tear samples; ocular inflammation ... See more keywords
3K3A-Activated Protein C Prevents Microglia Activation, Inhibits NLRP3 Inflammasome and Limits Ocular Inflammation
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DOI: 10.3390/ijms232214196
Abstract: 3K3A-Activated Protein C (APC) is a recombinant variant of the physiological anticoagulant APC with pleiotropic cytoprotective properties albeit without the bleeding risks. The anti-inflammatory activities of 3K3A-APC were demonstrated in multiple preclinical injury models, including… read more here.
Keywords: inflammation; 3k3a apc; ocular inflammation; treatment ... See more keywords
5-ALA/SFC Ameliorates Endotoxin-Induced Ocular Inflammation in Rats by Inhibiting the NF-κB Signaling Pathway and Activating the HO-1/Nrf2 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24108653
Abstract: Sodium ferrous citrate (SFC) is involved in the metabolism of 5-aminolevulinic acid (5-ALA) and enhances its anti-inflammatory effects. The effects of 5-ALA/SFC on inflammation in rats with endotoxin-induced uveitis (EIU) have yet to be elucidated.… read more here.
Keywords: ala sfc; ocular inflammation; ala; signaling pathway ... See more keywords