The m6A reading protein YTHDF3 potentiates tumorigenicity of cancer stem-like cells in ocular melanoma through facilitating CTNNB1 translation
Sign Up to like & getrecommendations! Published in 2022 at "Oncogene"
DOI: 10.1038/s41388-021-02146-0
Abstract: N6-methyladenosine (m6A) is the most universal internal RNA modification on messenger RNAs and regulates the fate and functions of m6A-modified transcripts through m6A-specific binding proteins. Nevertheless, the functional role and potential mechanism of the m6A… read more here.
Keywords: stem like; ocular melanoma; m6a reading; melanoma ... See more keywords
Ocular melanoma incidence rates and trends in the United States, 2001–2016
Sign Up to like & getrecommendations! Published in 2020 at "Eye"
DOI: 10.1038/s41433-020-0885-1
Abstract: Ocular melanoma is a rare form of melanoma (less than 5% of melanoma cases) arising from melanocytes of the uveal tract, conjunctiva, or orbit; however, up to 50% of patients will develop metastatic disease [1,… read more here.
Keywords: melanoma; incidence rates; 2001 2016; melanoma incidence ... See more keywords
Clinical features and survival outcomes of ocular melanoma in a multi-ethnic Asian cohort
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-73534-x
Abstract: Ocular melanomas are uncommon cancers in Southeast Asia unlike in the West. We conducted a retrospective review of patients (n = 44) with histologically-proven ocular melanoma within a multi-ethnic Asian cohort from Singapore. Clinicopathological features and relapse… read more here.
Keywords: melanoma; multi ethnic; cohort; ethnic asian ... See more keywords
The Patient's Experience of Ocular Melanoma in the US: A Survey of the Ocular Melanoma Foundation
Sign Up to like & getrecommendations! Published in 2018 at "Ocular Oncology and Pathology"
DOI: 10.1159/000485189
Abstract: Background: Ocular melanomas threaten patients with early death, visual handicap, and loss of the eye. The aims of this study were to identify aspects of care that patients with ocular melanoma considered most important and… read more here.
Keywords: melanoma; survey ocular; ocular melanoma; melanoma foundation ... See more keywords
Efficacy and Safety of Immune Checkpoint Blockades in the Treatment of Ocular Melanoma: A Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.781162
Abstract: Aim This meta-analysis aimed to compare the efficacy and safety of immune checkpoint blockade for the treatment of ocular melanoma. Methods We searched the PubMed, EMBASE, and Cochrane Library databases up to July 2021. Effect… read more here.
Keywords: safety; treatment; ocular melanoma; efficacy safety ... See more keywords