A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.08.073
Abstract: SUMMARY Id helix-loop-helix (HLH) proteins (Id1–4) bind E protein bHLH transcription factors, preventing them from forming active transcription complexes that drive changes in cell states. Id proteins are primarily expressed during development to inhibit differentiation,… read more here.
Keywords: ocular neovascularization; pan antagonist; small molecule; molecule pan ... See more keywords
Rosmarinic Acid Intravitreal Implants: A New Therapeutic Approach for Ocular Neovascularization.
Sign Up to like & getrecommendations! Published in 2020 at "Planta medica"
DOI: 10.1055/a-1223-2525
Abstract: Rosmarinic acid, a plant-derived compound with antiangiogenic activity, can be applied for the treatment of ocular diseases related to neovascularization, such as diabetic retinopathy, macular edema, and age-related macular degeneration. These diseases represent the leading… read more here.
Keywords: ocular neovascularization; acid; acid intravitreal; rosmarinic acid ... See more keywords
Risk factors for ocular neovascularization after central retinal artery occlusion
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Chinese Medical Association"
DOI: 10.1097/jcma.0000000000000766
Abstract: Background: To report the incidence and risk factors associated with ocular neovascularization (NV) in patients with central retinal artery occlusion (CRAO). Methods: This retrospective study included patients diagnosed with acute CRAO in a single tertiary… read more here.
Keywords: central retinal; retinal artery; risk factors; risk ... See more keywords
Potential epigenetic molecular regulatory networks in ocular neovascularization
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.970224
Abstract: Neovascularization is one of the many manifestations of ocular diseases, including corneal injury and vascular diseases of the retina and choroid. Although anti-VEGF drugs have been used to effectively treat neovascularization, long-term use of anti-angiogenic… read more here.
Keywords: potential epigenetic; molecular regulatory; regulatory networks; epigenetic molecular ... See more keywords