Ocular Pharmacokinetics.
Sign Up to like & getrecommendations! Published in 2017 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2016_32
Abstract: Although the fundamental concepts of pharmacokinetics remain the same, ocular pharmacokinetics has its own challenges due to the uniqueness of barrier properties posed by various ocular tissues and its growing complexity with different routes of… read more here.
Keywords: administration; physicochemical properties; ocular pharmacokinetics; pharmacology ... See more keywords
Ocular Pharmacokinetics of Intravitreally Injected Protein Therapeutics: Comparison among Standard-of-Care Formats.
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DOI: 10.1021/acs.molpharmaceut.0c01218
Abstract: The current standard of care for antivascular endothelial growth factor (VEGF) treatment requires frequent intravitreal (IVT) injections of protein therapeutics, as a result of limited retention within the eye. A thorough understanding of the determinants… read more here.
Keywords: pharmacokinetics intravitreally; protein therapeutics; ocular pharmacokinetics; care ... See more keywords
Comparative Study of Ocular Pharmacokinetics of Topical 0.3% Gatifloxacin Eye Gel and Solution in Rabbits
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DOI: 10.3390/antibiotics11040502
Abstract: Few articles have reported drug concentrations of different ophthalmic dosage forms in the ocular tissues. This study aimed to determine the ocular pharmacokinetics of gatifloxacin 0.3% eye gel (GTX-Gel) and gatifloxacin 0.3% eye solution (GTX-Sol)… read more here.
Keywords: gatifloxacin eye; ocular tissues; ocular pharmacokinetics; gatifloxacin ... See more keywords