Ocular toxicities associated with antibody drug conjugates
Sign Up to like & getrecommendations! Published in 2024 at "Current Opinion in Ophthalmology"
DOI: 10.1097/icu.0000000000001063
Abstract: Purpose of review To review the structure, mechanism of action, and pathophysiology of antibody-drug conjugates (ADCs) used to treat gynecological malignancies associated with ocular adverse effects. Recent findings Recent research shows tisotumab vedotin causes ocular… read more here.
Keywords: ocular adverse; ocular toxicities; adverse effects; antibody drug ... See more keywords
Ocular Toxicities of MEK Inhibitors in Patients With Cancer: A Systematic Review and Meta-analysis.
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DOI: 10.46883/2023.25920987
Abstract: BACKGROUND Mitogen-activated protein kinase (MEK) inhibitors, which integrate the important signaling chain of the RAS-RAF-MEK-ERK1/2 pathway, regulate cell functions such as division and proliferation for patients with solid tumors. However, various ocular adverse effects (AEs)… read more here.
Keywords: ocular toxicities; mek inhibitors; aes; systematic review ... See more keywords