Ocular toxicity of mustard gas: a concise review.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2021.02.007
Abstract: Sulfur mustard (SM) is a chemical warfare agent that has been used throughout recent history and remains a threat today. Exposed soldiers and civilians experience a variety of symptoms primarily in the respiratory system, skin,… read more here.
Keywords: mustard gas; mustard; review; ocular toxicity ... See more keywords
Late-onset Ocular Toxicity Presenting as Uveitis Caused by Crizotinib
Sign Up to like & getrecommendations! Published in 2021 at "Neuro-Ophthalmology"
DOI: 10.1080/01658107.2021.1876099
Abstract: A 64-year-old female suffering from lung cancer was treated with crizotinib. Two years later, whitish massive optic disc oedema was observed in the right eye. The fluorescein angiography results we... read more here.
Keywords: late onset; onset ocular; toxicity presenting; presenting uveitis ... See more keywords
Impact of belantamab mafodotin‐induced ocular toxicity on outcomes of patients with advanced multiple myeloma
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Haematology"
DOI: 10.1111/bjh.18298
Abstract: Belantamab mafodotin (BLMF) is a B‐cell maturation antigen‐directed antibody‐drug conjugate, recently approved for advanced multiple myeloma (MM). The impact of BLMF‐induced ocular toxicity on patient outcomes is unknown. We studied a cohort of 38 consecutively… read more here.
Keywords: advanced multiple; belantamab mafodotin; blmf; toxicity ... See more keywords
Modulation of Macropinocytosis-Mediated Internalization Decreases Ocular Toxicity of Antibody-Drug Conjugates.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer research"
DOI: 10.1158/0008-5472.can-17-3202
Abstract: AGS-16C3F is an antibody-drug conjugate (ADC) against ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) containing the mcMMAF linker-payload currently in development for treatment of metastatic renal cell carcinoma. AGS-16C3F and other ADCs have been reported to cause ocular… read more here.
Keywords: macropinocytosis; toxicity; ocular toxicity; antibody drug ... See more keywords
Ocular toxicity following carboplatin chemotherapy for neuroendocrine tumour of the bladder
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology Pharmacy Practice"
DOI: 10.1177/10781552221122005
Abstract: Introduction Carboplatin is a commonly used platinum analogue chemotherapeutic agent that is similar to cisplatin but is known to be better tolerated. This case report outlines a case of ocular toxicity following carboplatin chemotherapy used… read more here.
Keywords: carboplatin; following carboplatin; ocular toxicity; case ... See more keywords
Ocular toxicity of intravitreal melphalan for retinoblastoma in Chinese patients
Sign Up to like & getrecommendations! Published in 2019 at "BMC Ophthalmology"
DOI: 10.1186/s12886-019-1059-4
Abstract: BackgroundTo evaluate the efficacy, complications, and clinical characteristics, including the ocular toxicity, of intravitreal melphalan(IVM) treatment for vitreous seeding in Chinese retinoblastoma patients.MethodsThis was a retrospective, non-comparative analysis including 30 consecutive eyes of 23 patients… read more here.
Keywords: intravitreal melphalan; seed; toxicity; toxicity intravitreal ... See more keywords
Induced pluripotent stem cell-derived limbal epithelial cells (LiPSC) as a cellular alternative for in vitro ocular toxicity testing
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0179913
Abstract: Induced pluripotent stem cells hold great potential to produce unlimited amount of differentiated cells as cellular source for regenerative medicine but also for in vitro drug screening and cytotoxicity tests. Ocular toxicity testing is mandatory… read more here.
Keywords: epithelial cells; pluripotent stem; ocular toxicity; induced pluripotent ... See more keywords
Metallic Engineered Nanomaterials and Ocular Toxicity: A Current Perspective
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14050981
Abstract: The ocular surface, comprised of the transparent cornea, conjunctiva, and protective tear film, forms a protective barrier defending deeper structures of the eye from particulate matter and mechanical trauma. This barrier is routinely exposed to… read more here.
Keywords: metallic enms; metallic engineered; nanomaterials ocular; toxicity ... See more keywords