Structure and Enzymatic Activity of an Intellectual Disability-Associated Ornithine Decarboxylase Variant, G84R
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DOI: 10.1021/acsomega.2c04702
Abstract: Ornithine decarboxylase (ODC) is a rate-limiting enzyme for the synthesis of polyamines (PAs). PAs are required for proliferation, and increased ODC activity is associated with cancer and neural over-proliferation. ODC levels and activity are therefore… read more here.
Keywords: intellectual disability; ornithine decarboxylase; g84r; activity ... See more keywords