Coordinated expression of p300 and HDAC3 upregulates histone acetylation during dentinogenesis
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DOI: 10.1002/jcb.29470
Abstract: Cellular differentiation is caused by highly controlled modifications in the gene expression but rarely involves a change in the DNA sequence itself. Histone acetylation is a major epigenetic factor that adds an acetyl group to… read more here.
Keywords: dentinogenesis; histone acetylation; acetylation; odontoblast differentiation ... See more keywords
Cytokine Expression of Stem Cells Originating from the Apical Complex and Coronal Pulp of Immature Teeth
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Endodontics"
DOI: 10.1016/j.joen.2017.08.018
Abstract: Introduction: The aim of this study was to measure and compare the expression levels of cytokines from developing apical complex cells (DACCs) and dental pulp stem cells (DPSCs) of the immature tooth. Methods: DPSC‐conditioned medium… read more here.
Keywords: apical complex; expression; odontoblast differentiation; daccs ... See more keywords
NRP1 Accelerates Odontoblast Differentiation of Dental Pulp Stem Cells Through Classical Wnt/β-Catenin Signaling.
Sign Up to like & getrecommendations! Published in 2017 at "Cellular reprogramming"
DOI: 10.1089/cell.2017.0020
Abstract: Neuropilin-1 (NRP1) is one of the members of neuropilin family. It can combine with disparate ligands involved in regulating cell proliferation, apoptosis, and differentiation. The binding of NRP1 to Sema3A stimulates osteoblast differentiation through the… read more here.
Keywords: wnt catenin; differentiation; odontoblast differentiation; classical wnt ... See more keywords
The Role of Neuropilin-1-FYN Interaction in Odontoblast Differentiation of Dental Pulp Stem Cells.
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DOI: 10.1089/cell.2017.0041
Abstract: Abnormal odontoblast differentiation of dental pulp stem cells (DPSCs) caused by inflammation is closely related to the development of dental caries. Neuropilin-1 (NRP1) is one of the members of neuropilin family. It can combine with… read more here.
Keywords: dpscs; differentiation; odontoblast differentiation; dental pulp ... See more keywords
Wedelolactone Enhances Odontoblast Differentiation by Promoting Wnt/β-Catenin Signaling Pathway and Suppressing NF-κB Signaling Pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular reprogramming"
DOI: 10.1089/cell.2018.0004
Abstract: Wedelolactone is a multitarget natural plant compound with many pharmacological activities, including anti-inflammatory, anticancer, and antiosteoporosis. In this study, dental pulp stem cells (DPSCs) were treated with or without wedelolactone. We found that wedelolactone stimulated… read more here.
Keywords: catenin; signaling pathway; wedelolactone; odontoblast differentiation ... See more keywords
Rosuvastatin Regulates Odontoblast Differentiation by Suppressing NF-κB Activation in an Inflammatory Environment.
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DOI: 10.1089/cell.2018.0031
Abstract: Rosuvastatin is a synthetic statin of 3-hydroxy-methyl-3-glutamyl coenzyme A reductase inhibitor. It has pleiotropic characteristics including hepatic selectivity, minimal metabolism, inhibition of inflammation, and induction of osteoblast differentiation. In this study, dental pulp stem cells… read more here.
Keywords: rosuvastatin; regulates odontoblast; differentiation; odontoblast differentiation ... See more keywords
FGF Signaling Prevents the Terminal Differentiation of Odontoblasts
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DOI: 10.1177/0022034517691732
Abstract: Members of the fibroblast growth factor (FGF) family play essential and important roles in primary and reparative dentinogenesis, with conflicting results regarding their effects on odontoblast differentiation. Our recent studies showed that the effects of… read more here.
Keywords: pulp; fgf signaling; differentiation; odontoblast differentiation ... See more keywords
Effect of SOX2 on odontoblast differentiation of dental pulp stem cells.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular medicine reports"
DOI: 10.3892/mmr.2017.7812
Abstract: The present study aimed to investigate the effect of SOX2 on odontoblast differentiation of dental pulp stem cells (DPSCs), and to examine the potential application of DPSCs on dental restoration. SRY‑box 2 (SOX2) overexpression in… read more here.
Keywords: differentiation dpscs; dpscs; differentiation; odontoblast differentiation ... See more keywords