Concentration-Dependent Cellular Uptake of Graphene Oxide Quantum Dots Promotes the Odontoblastic Differentiation of Dental Pulp Cells via the AMPK/mTOR Pathway
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c06508
Abstract: As zero-dimension nanoparticles, graphene oxide quantum dots (GOQDs) have broad potential for regulating cell proliferation and differentiation. However, such regulation of dental pulp cells (DPSCs) with different concentrations of GOQDs is insufficiently investigated, especially on… read more here.
Keywords: odontoblastic differentiation; mtor; concentration; graphene oxide ... See more keywords
Role of connexin 43 in odontoblastic differentiation and structural maintenance in pulp damage repair
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Oral Science"
DOI: 10.1038/s41368-020-00105-1
Abstract: Dental pulp can initiate its damage repair after an injury of the pulp–dentin complex by rearrangement of odontoblasts and formation of newly differentiated odontoblast-like cells. Connexin 43 (Cx43) is one of the gap junction proteins… read more here.
Keywords: cx43; odontoblastic differentiation; pulp; damage repair ... See more keywords
Klf5 Mediates Odontoblastic Differentiation through Regulating Dentin-Specific Extracellular Matrix Gene Expression during Mouse Tooth Development
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DOI: 10.1038/srep46746
Abstract: Klf5, a member of the Krüppel-like transcription factor family, has essential roles during embryonic development, cell proliferation, differentiation, migration and apoptosis. This study was to define molecular mechanism of Klf5 during the odontoblastic differentiation. The… read more here.
Keywords: mouse tooth; differentiation; klf5; odontoblastic differentiation ... See more keywords
Reactive oxygen species induced-inhibition of odontoblastic differentiation of mouse dental papilla cells is mediated by downregulation of importin 7.
Sign Up to like & getrecommendations! Published in 2023 at "Stem cells and development"
DOI: 10.1089/scd.2022.0297
Abstract: Tooth dentin is a crucial tooth structure. The biological process of odontoblast differentiation is essential for formation of normal dentin. The accumulation of reactive oxygen species (ROS) leads to oxidative stress, which can influence the… read more here.
Keywords: mouse dental; dental papilla; odontoblastic differentiation; papilla cells ... See more keywords
Expression of KLF5 in odontoblastic differentiation of dental pulp cells during in vitro odontoblastic induction and in vivo dental repair
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DOI: 10.1111/iej.12672
Abstract: AIM To identify whether Krüppel-like factor 5 (KLF5) was involved in odontoblastic differentiation during reparative dentine formation. METHODOLOGY Human Dental pulp cells (DPCs) were isolated from healthy human dental pulp tissue and induced for odontoblastic… read more here.
Keywords: differentiation; dental pulp; odontoblastic differentiation; dentine ... See more keywords
Mineral Trioxide Aggregate-induced AMPK Activation Stimulates Odontoblastic Differentiation of Human Dental Pulp Cells.
Sign Up to like & getrecommendations! Published in 2020 at "International endodontic journal"
DOI: 10.1111/iej.13460
Abstract: AIM To investigate the role of autophagy in MTA-induced odontoblastic differentiation of human dental pulp cells (HDPCs). METHODOLOGY In MTA-treated HDPCs, odontoblastic differentiation was assessed based on expression levels of dentine sialophosphoprotein (DSPP) and dentine… read more here.
Keywords: differentiation human; mta induced; ampk; differentiation ... See more keywords
3D Spheroid Formation Using BMP-Loaded Microparticles Enhances Odontoblastic Differentiation of Human Dental Pulp Stem Cells
Sign Up to like & getrecommendations! Published in 2021 at "Stem Cells International"
DOI: 10.1155/2021/9326298
Abstract: Human dental pulp stem cells (hDPSCs) are the primary cells responsible for dentin regeneration. Typically, in order to allow for odontoblastic differentiation, hDPSCs are cultured over weeks with differentiation-inducing factors in a typical monolayered culture.… read more here.
Keywords: human dental; differentiation; dental pulp; odontoblastic differentiation ... See more keywords
WWP2 Promotes Odontoblastic Differentiation by Monoubiquitinating KLF5
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DOI: 10.1177/0022034520970866
Abstract: WW domain-containing E3 Ub-protein ligase 2 (WWP2) belongs to the homologous to E6AP C-terminus (HECT) E3 ligase family. It has been explored to regulate osteogenic differentiation, chondrogenesis, and palatogenesis. Odontoblasts are terminally differentiated mesenchymal cells,… read more here.
Keywords: wwp2; differentiation; odontoblastic differentiation; differentiation monoubiquitinating ... See more keywords
Promotive Effect of FBXO32 on the Odontoblastic Differentiation of Human Dental Pulp Stem Cells
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DOI: 10.3390/ijms24097708
Abstract: Odontoblastic differentiation of human dental pulp stem cells (hDPSCs) is crucial for the intricate formation and repair processes in dental pulp. Until now, the literature is not able to demonstrate the role of ubiquitination in… read more here.
Keywords: dental pulp; odontoblastic differentiation; hdpscs; human dental ... See more keywords
RORα Regulates Odontoblastic Differentiation and Mediates the Pro-Odontogenic Effect of Melatonin on Dental Papilla Cells
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DOI: 10.3390/molecules26041098
Abstract: Dental papilla cells (DPCs), precursors of odontoblasts, are considered promising seed cells for tissue engineering. Emerging evidence suggests that melatonin promotes odontoblastic differentiation of DPCs and affects tooth development, although the precise mechanisms remain unknown.… read more here.
Keywords: ror; pro odontogenic; odontogenic effect; differentiation ... See more keywords
Hypoxia‑induced mitophagy regulates proliferation, migration and odontoblastic differentiation of human dental pulp cells through FUN14 domain‑containing 1.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of molecular medicine"
DOI: 10.3892/ijmm.2022.5128
Abstract: FUN14 domain‑containing 1 (FUNDC1) is a receptor that has been previously reported to activate hypoxia‑induced mitophagy. However, the potential role of FUNDC1 in the pathophysiology of dental pulp diseases remains unknown. Therefore, present study first… read more here.
Keywords: differentiation; migration; odontoblastic differentiation; migration odontoblastic ... See more keywords