Sodium fluoride regulates the osteo/odontogenic differentiation of stem cells from apical papilla by modulating autophagy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28269
Abstract: Fluoride (sodium fluoride) is thought to be essential in the development of tooth, and research shows that fluoride can modulate the differentiation of dental stem cells. However, the effects of fluoride on the committed differentiation… read more here.
Keywords: sodium fluoride; odontogenic differentiation; differentiation; osteo odontogenic ... See more keywords
Parathyroid hormone enhances the osteo/odontogenic differentiation of dental pulp stem cells via ERK and P38 MAPK pathways
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29034
Abstract: Parathyroid hormone (PTH) is a main systemic mediator of calcium and phosphate homeostasis in the bone. Dental pulp stem cells (DPSCs) have been extensively studied in the regeneration of bone and tooth tissues. This paper… read more here.
Keywords: parathyroid hormone; odontogenic differentiation; dental pulp; pulp stem ... See more keywords
Leptin Induces Odontogenic Differentiation and Angiogenesis in Human Dental Pulp Cells via Activation of the Mitogen‐activated Protein Kinase Signaling Pathway
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Endodontics"
DOI: 10.1016/j.joen.2017.11.018
Abstract: Introduction: Up‐regulation of odontogenic differentiation, dentin formation, and angiogenesis in dental pulp are key factors in vital pulp therapy. The aim of this study was to investigate whether leptin could promote odontogenic differentiation and angiogenesis… read more here.
Keywords: differentiation angiogenesis; differentiation; dental pulp; odontogenic differentiation ... See more keywords
Gelatin/bioactive glass composite scaffold for promoting the migration and odontogenic differentiation of bone marrow mesenchymal stem cells
Sign Up to like & getrecommendations! Published in 2021 at "Polymer Testing"
DOI: 10.1016/j.polymertesting.2020.106915
Abstract: Abstract Recruiting periapical stem cells into the root canal and inducing their odontogenic differentiation are both vital for pulp regeneration. This study was aimed at developing a kind of bioactive composite scaffolds (G/PSC scaffolds) by… read more here.
Keywords: bioactive glass; stem cells; psc scaffold; odontogenic differentiation ... See more keywords
miR‐675 promotes odontogenic differentiation of human dental pulp cells by epigenetic regulation of DLX3
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2018.03.035
Abstract: ABSTRACT In a previous study, we showed that microRNA‐675 (miR‐675) was significantly down‐regulated in patients with tricho‐dento‐osseous (TDO) syndrome. One of the main features of TDO syndrome is dentin hypoplasia. Thus, we hypothesize that miR‐675… read more here.
Keywords: dlx3; differentiation human; odontogenic differentiation; hdpcs ... See more keywords
General Control Nonrepressed Protein 5 Modulates Odontogenic Differentiation Through NF-κB Pathway in Tumor Necrosis Factor-α-Mediated Impaired Human Dental Pulp Stem Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular reprogramming"
DOI: 10.1089/cell.2021.0113
Abstract: Dental pulp stem cells (DPSCs) from pulpitis patients showed defective osteogenic differentiation. However, as the most well-studied histone acetyltransferase, the impaired general control nonrepressed protein 5 (GCN5) plays essential roles in various developmental processes. The… read more here.
Keywords: dental pulp; dpscs; odontogenic differentiation; gcn5 ... See more keywords
Adrenomedullin promotes the odontogenic differentiation of dental pulp stem cells through CREB/BMP2 signaling pathway
Sign Up to like & getrecommendations! Published in 2017 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.1093/abbs/gmx053
Abstract: Adrenomedullin (AM) could promote the proliferation, the odontogenic differentiation and inhibit the apoptosis of dental pulp stem cells (DPSCs). AM in combination with DPSCs may be an effective strategy for pulp repair. However, there was… read more here.
Keywords: differentiation dpscs; differentiation; dental pulp; odontogenic differentiation ... See more keywords
PD-1 suppresses the osteogenic and odontogenic differentiation of stem cells from dental apical papilla via targeting SHP2/NF-κB axis.
Sign Up to like & getrecommendations! Published in 2022 at "Stem cells"
DOI: 10.1093/stmcls/sxac037
Abstract: Stem cells from the apical papilla (SCAPs) are important for tooth root development and regeneration of root dentin. Here, we examined the expression of programmed cell death protein-1 (PD-1) in SCAPs and investigated the effect… read more here.
Keywords: differentiation; odontogenic differentiation; apical papilla; stem cells ... See more keywords
A connectivity mapping approach predicted acetylsalicylic acid (aspirin) to induce osteo/odontogenic differentiation of dental pulp cells.
Sign Up to like & getrecommendations! Published in 2020 at "International endodontic journal"
DOI: 10.1111/iej.13281
Abstract: AIM To use the connectivity map, a bioinformatics approach, to identify compounds that could induce odontogenic differentiation of dental pulp cells (DPCs) and to experimentally validate this effect. A subsidiary aim was to investigate the… read more here.
Keywords: connectivity; odontogenic differentiation; expression; differentiation ... See more keywords
Effects of phase-transited lysozyme on adhesion, migration, and odontogenic differentiation of human dental pulp cells: An in vitro study.
Sign Up to like & getrecommendations! Published in 2022 at "International endodontic journal"
DOI: 10.1111/iej.13884
Abstract: AIM To explore the effects of phase-transited lysozyme (PTL) coated dentine slices on cell adhesion, migration and odontogenic differentiation of human dental pulp cells (HDPCs). METHODOLOGY Cell growth and cell cycle analysis were conducted to… read more here.
Keywords: adhesion; cell; odontogenic differentiation; migration ... See more keywords
Follicle‐stimulating hormone impairs dental pulp stem cells odontogenic differentiation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15681
Abstract: In addition to bone, the dentin‐pulp complex is also influenced by menopause, showing a decreased regenerative capacity. High levels of follicle‐stimulating hormone (FSH) during menopause could directly regulate bone metabolism. Here, the role of FSH… read more here.
Keywords: follicle stimulating; odontogenic differentiation; differentiation; fsh ... See more keywords