Cerebral oxygen metabolic stress is increased in children with sickle cell anemia compared to anemic controls
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26485
Abstract: Patients with sickle cell anemia (SCA) experience cerebral metabolic stress with an increase in oxygen extraction fraction (OEF) to compensate for reduced oxygen carrying capacity due to anemia. It remains unclear if anemia alone drives… read more here.
Keywords: sca; metabolic stress; oef; oxygen ... See more keywords
Correlation Between Cerebral Tissue Oxygen Saturation and Oxygen Extraction Fraction During Anesthesia: Monitoring Cerebral Metabolic Demand-supply Balance During Vasopressor Administration.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of neurosurgical anesthesiology"
DOI: 10.1097/ana.0000000000000822
Abstract: BACKGROUND The speculation that cerebral tissue oxygen saturation (SctO2) measured using tissue near-infrared spectroscopy reflects the balance between cerebral metabolic rate of oxygen and cerebral oxygen delivery has not been validated. Our objective was to… read more here.
Keywords: balance; treatment; tissue; oef ... See more keywords
Normalization of cerebral hemodynamics following hematopoietic stem cell transplant in children with sickle cell disease.
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DOI: 10.1182/blood.2022016618
Abstract: Children with sickle cell disease (SCD) demonstrate cerebral hemodynamic stress and are at high risk of strokes. We hypothesized that curative hematopoietic stem cell transplant (HSCT) normalizes cerebral hemodynamics in children with SCD compared to… read more here.
Keywords: cell; hsct; children sickle; cbf ... See more keywords