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Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2019.10.036
Abstract: Oesophago-gastric cancers (OGCs) are aggressive tumours. While better peri-operative strategies, increased number of cytotoxic agents and availability of targeted therapies have improved survival, there remains an unmet need for novel treatment approaches. Immune checkpoint inhibitors…
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Keywords:
inhibitors oesophago;
ogc;
gastric cancers;
oesophago gastric ... See more keywords
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Published in 2020 at "Expert Review of Anticancer Therapy"
DOI: 10.1080/14737140.2021.1866548
Abstract: ABSTRACT Introduction Esophagogastric cancers remain a considerable health burden and among the top causes of global cancer-related deaths. Chemotherapy remains the cornerstone of treatment for patients with advanced disease. Doublet platinum/fluoropyrimidine therapy is established as…
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Keywords:
gastric cancers;
oesophago gastric;
treatment;
therapies advanced ... See more keywords
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Published in 2021 at "British Journal of Surgery"
DOI: 10.1093/bjs/znab117.061
Abstract: High quality surgery remains the cornerstone of treating oesophago-gastric malignancy. Recent work from the Dutch Upper-gastrointestinal Cancer Audit (DUCA) have defined ten surgical and perioperative ‘textbook’ parameters that correlate with improved overall survival. The aim…
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Keywords:
textbook;
oesophago gastric;
post kpi;
cancer ... See more keywords
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Published in 2021 at "Therapeutic Advances in Medical Oncology"
DOI: 10.1177/17588359211065153
Abstract: Background: Perioperative chemotherapy is a recommended treatment approach for localised oesophago-gastric junction adenocarcinoma, but not all patients respond to neoadjuvant chemotherapy. Early identification of non-responders and treatment adaptation in the preoperative period could improve outcomes.…
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Keywords:
gastric junction;
treatment;
feasibility;
pet ... See more keywords
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Published in 2022 at "Cancers"
DOI: 10.3390/cancers14030586
Abstract: Simple Summary Oesophageal (food pipe) and stomach cancers are amongst the hard-to-treat cancers that result in significant illness and deaths around the globe. Over the last few decades, there has been remarkable progress in the…
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Keywords:
gastric adenocarcinoma;
multimodality;
resectable oesophago;
oesophago gastric ... See more keywords