Oestrogen receptor α in T cells controls the T cell immune profile and glucose metabolism in mouse models of gestational diabetes mellitus
Sign Up to like & getrecommendations! Published in 2021 at "Diabetologia"
DOI: 10.1007/s00125-021-05447-x
Abstract: The imbalance between maternal insulin resistance and a relative lack of insulin secretion underlies the pathogenesis of gestational diabetes mellitus (GDM). Alterations in T cell subtypes and increased levels of circulating proinflammatory cytokines have been… read more here.
Keywords: insulin; oestrogen; gdm; gdm mice ... See more keywords
Controversy in the management of oestrogen therapy before hysteroscopic adhesiolysis: a systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive biomedicine online"
DOI: 10.1016/j.rbmo.2020.06.012
Abstract: The aim of this systematic review and meta-analysis was to assess the effect of oestrogen therapy as a preoperative intervention for improving clinical outcomes and fertility outcomes in women with intrauterine adhesions (IUA). A systematic… read more here.
Keywords: oestrogen therapy; oestrogen; systematic review; meta analysis ... See more keywords
Sitting, physical activity, and serum oestrogen metabolism in postmenopausal women: the Women’s Health Initiative Observational Study
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Cancer"
DOI: 10.1038/bjc.2017.268
Abstract: Background:Prolonged sitting and lower levels of physical activity have been associated with increased levels of parent oestrogens (oestrone and oestradiol), the key hormones in female cancers, in postmenopausal women. However, it is unknown whether sitting… read more here.
Keywords: oestrogen; activity associated; parent oestrogens; physical activity ... See more keywords
Oestrogen dose tapering during luteal phase does not affect clinical outcomes after hormone replacement treatment-frozen-thawed embryo transfer cycles: a retrospective analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Human reproduction"
DOI: 10.1093/humrep/dez096
Abstract: STUDY QUESTION Does oestrogen dose tapering during the luteal phase affect the clinical outcome after hormone replacement treatment-frozen-thawed embryo transfer (HRT-FET) cycles? SUMMARY ANSWER Our results suggest that tapering oestrogen doses during the luteal phase… read more here.
Keywords: phase; fet cycles; oestrogen; luteal phase ... See more keywords
The Effect of Oestrogen Supplementation on Antioxidant Enzymes and Mitochondrial Respiratory Function After Myocardial Infarction of Ovariectomized Rats
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000001224
Abstract: Abstract: Acute myocardial infarction (MI) is the leading cause of mortality worldwide with premenopausal women showing a lower incidence of cardiovascular disease compared with men of the same age. After menopause, this advantage disappears, suggesting… read more here.
Keywords: supplementation; function; oestrogen; respiratory function ... See more keywords
Oestrogen promotes tumorigenesis of bladder cancer by inducing the enhancer RNA—eGREB1
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.13861
Abstract: In recent years, studies have shown that enhancer RNAs (eRNAs) can be transcribed from enhancers. Increasing evidence has revealed that eRNAs play critical roles in the development of various cancers. Oestrogen‐associated eRNAs are closely related… read more here.
Keywords: bladder cancer; oestrogen; bca; egreb1 ... See more keywords
Localisation of oestrogen receptors in stem cells and in stem cell‐derived neurons of the mouse
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroendocrinology"
DOI: 10.1111/jne.13220
Abstract: Oestrogen receptors (ER) transduce the effects of the endogenous ligand, 17β‐estradiol in cells to regulate a number of important processes such as reproduction, neuroprotection, learning and memory and anxiety. The ERα or ERβ are classical… read more here.
Keywords: neurons mouse; oestrogen; oestrogen receptors; localisation oestrogen ... See more keywords
Possible association of oestrogen and Cryba4 with masticatory muscle tendon-aponeurosis hyperplasia.
Sign Up to like & getrecommendations! Published in 2019 at "Oral diseases"
DOI: 10.1111/odi.12876
Abstract: OBJECTIVE Masticatory muscle tendon-aponeurosis hyperplasia, which is associated with limited mouth opening, progresses very slowly from adolescence. The prevalence rates of this disease are higher among women than among men, suggesting oestrogen involvement. As parafunctional… read more here.
Keywords: oestrogen; muscle tendon; cryba4; tendon aponeurosis ... See more keywords
GP141 Possible aggravation of desmoid tumours with primary ovarian failure treatment
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2019-epa.205
Abstract: Introduction Chromosomal abnormalities are a common cause of primary ovarian failure in adolescents. Familial adenomatous polyposis (FAP) is an autosomal dominant predisposition to developing colonic polyposis arising from a germline mutation in the APC gene.… read more here.
Keywords: treatment; oestrogen; failure; desmoid tumours ... See more keywords
Notch activity mediates oestrogen-induced stromal cell invasion in endometriosis.
Sign Up to like & getrecommendations! Published in 2018 at "Reproduction"
DOI: 10.1530/rep-18-0326
Abstract: Oestrogen has been reported to control the invasiveness of endometrial stromal cells in endometriosis. Notch signalling, a master regulator of cell invasion in tumours, is regulated by oestrogen in other diseases and hyperactivated in endometriotic… read more here.
Keywords: notch activity; oestrogen; cell; cell invasion ... See more keywords
Design and optimization of oestrogen receptor PROTACs based on 4-hydroxytamoxifen.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of medicinal chemistry"
DOI: 10.2139/ssrn.4126049
Abstract: In the last four decades, treatment of oestrogen receptor positive (ER+) breast cancer (BCa), has focused on targeting the estrogenic receptor signaling pathway. This signaling function is pivotal to sustain cell proliferation. Tamoxifen, a competitive… read more here.
Keywords: oestrogen receptor; oestrogen; protacs; based hydroxytamoxifen ... See more keywords