Sargassum integerrimum inhibits oestrogen deficiency and hyperlipidaemia-induced bone loss by upregulating nuclear factor (erythroid-derived 2)-like 2 in female rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Orthopaedic Translation"
DOI: 10.1016/j.jot.2019.03.002
Abstract: Ethnopharmacological relevance Oestrogen deficiency, high incidences of hyperlipidaemia (HLP) and accelerated bone loss frequently occur in postmenopausal women. There is an urgent need to develop functional foods or specific drugs to protect against bone loss… read more here.
Keywords: oestrogen deficiency; bone; nuclear factor; bone loss ... See more keywords
Influence of oestrogen deficiency and excessive mechanical stress on condylar head of mandible.
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DOI: 10.1111/odi.13452
Abstract: OBJECTIVE We assessedthe etiology of idiopathic condylar resorptionby examining the effects of oestrogen and compressive mechanical stress under a low systemic oestrogen condition in temporomandibular joints (TMJ) caused by an ovariectomy. MATERIALS AND METHODS Female… read more here.
Keywords: mechanical stress; influence oestrogen; stress; deficiency excessive ... See more keywords
α-Asarone Attenuates Osteoclastogenesis and Prevents Against Oestrogen-Deficiency Induced Osteoporosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.780590
Abstract: Osteoporosis (OP) is defined as low bone mineral density which features over activated osteoclasts (OCs) and bone resorption. Targeting excessive OCs activity is thought to be an effective therapeutic approach for OP treatment. α-asarone (ASA),… read more here.
Keywords: resorption; oestrogen deficiency; bone; osteoclastogenesis ... See more keywords