Conditioned pain modulation and offset analgesia: Influence of sex, sex hormone levels and menstrual cycle on the magnitude and retest reliability in healthy participants
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DOI: 10.1002/ejp.2014
Abstract: Conditioned pain modulation (CPM) and offset analgesia quantify impairment of endogenous pain modulation, but magnitude and reliability vary broadly between studies, indicating influencing factors that are not currently controlled for. The aim of this study… read more here.
Keywords: offset analgesia; magnitude; reliability; sex ... See more keywords
Neural Mechanisms of Offset Analgesia.
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DOI: 10.1007/978-981-13-1756-9_12
Abstract: One feels a disproportionately large decrease of pain sensation on a slight decrease of thermal pain stimulus. Such phenomenon is termed offset analgesia and considered mediated by endogenous analgesic mechanisms. Offset analgesia was found attenuated… read more here.
Keywords: mechanisms offset; offset analgesia; neural mechanisms; biology ... See more keywords
Pain sensitivity and experimentally induced sensitization in red haired women
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DOI: 10.1016/j.sjpain.2010.05.012
Abstract: oop adjusted the laser power. 8 subjects participated in this study. timulations were applied on the dorsum side and in the palm of the and. Subjects were instructed to continuously rate the pain intenity. First… read more here.
Keywords: experimentally induced; induced sensitization; pain sensitivity; offset analgesia ... See more keywords
Disrupted offset analgesia distinguishes patients with chronic pain from healthy controls
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DOI: 10.1097/j.pain.0000000000000989
Abstract: Abstract Offset analgesia (OA) represents a disproportionately large decrease of pain perception after a brief, temporary increment of thermal pain stimulus and was reported attenuated in patients with neuropathic pain. We examined whether OA depends… read more here.
Keywords: pain healthy; healthy controls; offset analgesia; patients chronic ... See more keywords
Offset analgesia and onset hyperalgesia with different stimulus ranges
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DOI: 10.1097/pr9.0000000000000914
Abstract: A comparison between the effects of offset analgesia and onset hyperalgesia and how these effects relate to the stimulus range of thermal stimulation. read more here.
Keywords: analgesia onset; hyperalgesia different; offset analgesia; different stimulus ... See more keywords
Offset analgesia is increased intra-orally.
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DOI: 10.1111/joor.13356
Abstract: BACKGROUND Offset analgesia (OA) is commonly used to quantify endogenous pain inhibition. However, the potential role of afferent inputs and the subsequent peripheral factors from different body areas on the underlying mechanisms are still unclear.… read more here.
Keywords: intra orally; analgesia; increased intra; offset analgesia ... See more keywords
Offset analgesia is associated with opposing modulation of medial versus dorsolateral prefrontal cortex activations: A functional near-infrared spectroscopy study
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Pain"
DOI: 10.1177/17448069221074991
Abstract: Offset analgesia is defined by a dramatic drop in perceived pain intensity with a relatively small decrease in noxious input. Although functional magnetic resonance imaging studies implicate subcortical descending inhibitory circuits during offset analgesia, the… read more here.
Keywords: functional near; offset analgesia; spectroscopy; prefrontal cortex ... See more keywords
Onset hyperalgesia and offset analgesia: Transient increases or decreases of noxious thermal stimulus intensity robustly modulate subsequent perceived pain intensity
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DOI: 10.1371/journal.pone.0231124
Abstract: Reported pain intensity depends not only on stimulus intensity but also on previously experienced pain. A painfully hot temperature applied to the skin evokes a lower subjective pain intensity if immediately preceded by a higher… read more here.
Keywords: pain intensity; onset hyperalgesia; stimulus; offset analgesia ... See more keywords
Psychological mechanisms of offset analgesia: The effect of expectancy manipulation
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DOI: 10.1371/journal.pone.0280579
Abstract: A frequently used paradigm to quantify endogenous pain modulation is offset analgesia, which is defined as a disproportionate large reduction in pain following a small decrease in a heat stimulus. The aim of this study… read more here.
Keywords: suggestion; offset analgesia; group; pain ... See more keywords