Prenatal stress effects on offspring brain and behavior: Mediators, alterations and dysregulated epigenetic mechanisms.
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DOI: 10.1007/s12038-021-00153-7
Abstract: Prenatal environment significantly influences mammalian fetal development and adverse in utero conditions have life-long consequences for the offspring health. Research has revealed that a wide variety of prenatal stress factors lead to increased risk of… read more here.
Keywords: offspring brain; alterations offspring; stress; stress effects ... See more keywords
Inflammatory Consequences of Maternal Diabetes on the Offspring Brain: a Hippocampal Organotypic Culture Study
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DOI: 10.1007/s12640-019-00070-6
Abstract: Gestational diabetes is a disorder associated with abnormal chronic inflammation that poses a risk to the developing fetus. We investigated the effects of experimentally induced diabetes (streptozotocin model) in Wistar female rats on the inflammatory… read more here.
Keywords: diabetic cultures; inflammatory; maternal diabetes; offspring brain ... See more keywords
Regulatory Effects of Maternal Immune Activation and Environmental Enrichment on Glucocorticoid Receptor and FKBP5 Expression in Stress-sensitive Regions of the Offspring Brain
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DOI: 10.2139/ssrn.3969056
Abstract: A mother's exposure to immune challenge during pregnancy is well known to be a detrimental factor to the development of the offspring's brain and an impetus for neuropsychiatric disorders. Previous studies have shown that these… read more here.
Keywords: stress; glucocorticoid receptor; receptor fkbp5; offspring brain ... See more keywords
Impact of Maternal Ketogenic Diet on NLRP3 Inflammasome Response in the Offspring Brain
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DOI: 10.3390/nu15081994
Abstract: The effects of maternal diet on the neuroimmune responses of the offspring remain to be elucidated. We investigated the impact of maternal ketogenic diet (KD) on the NLRP3 inflammasome response in the offspring’s brain. C57BL/6… read more here.
Keywords: compared group; offspring brain; brain; group ... See more keywords