The added value of rodent models in studying parental influence on offspring development: opportunities, limitations and future perspectives.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in psychology"
DOI: 10.1016/j.copsyc.2017.02.030
Abstract: Over the past decades, the influence of parental care on offspring development has been a topic of extensive research in both human and animal models. Rodent models offer several unique advantages over human studies, allowing… read more here.
Keywords: added value; rodent models; influence; offspring development ... See more keywords
Maternal stress and the maternal microbiome have sex-specific effects on offspring development and aggressive behavior in Siberian hamsters (Phodopus sungorus)
Sign Up to like & getrecommendations! Published in 2022 at "Hormones and Behavior"
DOI: 10.1016/j.yhbeh.2022.105146
Abstract: The gut microbiome, a community of commensal, symbiotic and pathogenic bacteria, fungi, and viruses, interacts with many physiological systems to affect behavior. Prenatal experiences, including exposure to maternal stress and different maternal microbiomes, are important… read more here.
Keywords: development; offspring development; stress; maternal microbiome ... See more keywords
Parental exposure to perfluorobutanesulfonate impairs offspring development through inheritance of paternal methylome.
Sign Up to like & getrecommendations! Published in 2019 at "Environmental science & technology"
DOI: 10.1021/acs.est.9b03865
Abstract: Perfluorobutanesulfonate (PFBS), an environmental pollutant of emerging concern, significantly impairs offspring development and overall health after parental exposure. However, the true inducer of offspring developmental defects among the complexity of parental influences remains unknown. In… read more here.
Keywords: parental exposure; perfluorobutanesulfonate; inheritance; impairs offspring ... See more keywords
Chronic testicular Chlamydia muridarum infection impairs mouse fertility and offspring development†
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioz229
Abstract: Abstract With approximately 131 million new genital tract infections occurring each year, Chlamydia is the most common sexually transmitted bacterial pathogen worldwide. Male and female infections occur at similar rates and both cause serious pathological… read more here.
Keywords: infection; testicular chlamydia; chlamydia; chronic testicular ... See more keywords
Paternal epigenetic influences on placental health and their impacts on offspring development and disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1068408
Abstract: Our efforts to understand the developmental origins of birth defects and disease have primarily focused on maternal exposures and intrauterine stressors. Recently, research into non-genomic mechanisms of inheritance has led to the recognition that epigenetic… read more here.
Keywords: health; male; growth; development ... See more keywords
Metformin during Pregnancy: Effects on Offspring Development and Metabolic Function
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.00653
Abstract: Maternal obesity during pregnancy and gestational diabetes mellitus (GDM) are both associated with of several postnatal diseases in the offspring, including obesity, early onset hypertension, diabetes mellitus, and reproductive alterations. Metformin is an oral drug… read more here.
Keywords: pregnancy; metformin pregnancy; obesity; offspring development ... See more keywords