Desflurane and Surgery Exposure During Pregnancy Decrease Synaptic Integrity and Induce Functional Deficits in Juvenile Offspring Mice
Sign Up to like & getrecommendations! Published in 2019 at "Neurochemical Research"
DOI: 10.1007/s11064-019-02932-z
Abstract: Anesthesia in pregnant women may cause adverse effects in the hippocampus of unborn babies and fetal brain development. The mechanisms underlying pathological changes resulting from anesthetics are unclear. This study tested the hypothesis that exposure… read more here.
Keywords: pregnancy; offspring mice; exposure; juvenile offspring ... See more keywords
Maternal exposure to perfluorooctanoic acid (PFOA) causes liver toxicity through PPAR-α pathway and lowered histone acetylation in female offspring mice
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-019-05258-z
Abstract: The study was conducted to investigate the liver toxicity in female offspring mice induced by maternal exposure to perfluorooctanoic acid (PFOA). Fifty pregnant Kunming mice were randomly divided into 5 groups with 10 of each,… read more here.
Keywords: liver toxicity; pfoa; offspring mice; maternal exposure ... See more keywords
Maternal immune activation alters visual acuity and retinogeniculate axon pruning in offspring mice
Sign Up to like & getrecommendations! Published in 2020 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2020.08.017
Abstract: Individuals with autism spectrum disorder (ASD) have been found to have a variety of sensory processing deficits. Here we report that maternal immune activation, a known factor for ASD, impairs visual acuity in the offspring… read more here.
Keywords: immune activation; maternal immune; acuity; offspring mice ... See more keywords
Maternal anesthesia with sevoflurane during the mid-gestation induces social interaction deficits in offspring C57BL/6 mice.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.03.063
Abstract: Sevoflurane anesthesia in pregnant mice could induce neurotoxicity in the developing brain and disturb learning and memory in the offspring mice. Whether it could impair social behaviors in the offspring mice is uncertain. Therefore, we… read more here.
Keywords: offspring mice; anesthesia; mice; social interaction ... See more keywords
Effects of PM2.5 exposure in utero on heart injury, histone acetylation and GATA4 expression in offspring mice.
Sign Up to like & getrecommendations! Published in 2020 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2020.127133
Abstract: Atmospheric fine particulate matter exposure (PM2.5) can increase the incidence and mortality of heart disease, and raise the risk of fetal congenital heart defect, which have recently drawn much attention. In this study, C57BL/6 mice… read more here.
Keywords: heart; offspring mice; exposure; gata4 ... See more keywords
Effects of maternal exposure to PFOA on testes of male offspring mice.
Sign Up to like & getrecommendations! Published in 2021 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2021.129585
Abstract: This study was conducted to explore the effects of maternal exposure to perfluorooctanoic acid (PFOA) on testicular development of male offspring mice. 20 pregnant Kunming mice were randomly divided into control group and PFOA exposure… read more here.
Keywords: pfoa; offspring mice; exposure; effects maternal ... See more keywords
Deleterious effects in reproduction and developmental immunity elicited by pulmonary iron oxide nanoparticles
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Research"
DOI: 10.1016/j.envres.2016.08.025
Abstract: Abstract With the extensive application of iron oxide nanoparticles (FeNPs), attention about their potential risks to human health is also rapidly raising, particularly in sensitive subgroups such as pregnant women and babies. In this study,… read more here.
Keywords: female parent; male female; offspring mice; parent mice ... See more keywords
Health Effects of Dietary Oxidized Milk Administration in Offspring Mice during Pregnancy and Lactation with Metabolomic Strategies.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c07132
Abstract: Milk is an important source of nutrients during pregnancy. Previous studies have consistently shown that oxidation in milk and dairy products can induce oxidative stress, inflammation, and fibrosis in the liver and kidney. However, the… read more here.
Keywords: metabolism; health; oxidized milk; offspring mice ... See more keywords
Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1707337115
Abstract: Significance Aging-associated diseases are increasingly common in an aging global population. However, the contributors and origins of differential risk for unhealthy aging remain poorly understood. Using a mouse model, we found that offspring of aged… read more here.
Keywords: offspring mice; pathology; old father; life span ... See more keywords
Bisphenol A Exposure during Pregnancy Alters the Mortality and Levels of Reproductive Hormones and Genes in Offspring Mice
Sign Up to like & getrecommendations! Published in 2017 at "BioMed Research International"
DOI: 10.1155/2017/3585809
Abstract: The present study investigated the reproductive toxicity of bisphenol A (BPA) exposure to the mother on the offspring mice. BPA was given to pregnant mice at 50 mg/kg, 500 mg/kg, and 2500 mg/kg BW BPA daily by gavage… read more here.
Keywords: bisphenol; bpa; offspring mice; exposure ... See more keywords
Maternal testosterone excess contributes to reproductive system dysfunction of female offspring mice.
Sign Up to like & getrecommendations! Published in 2019 at "Endocrinology"
DOI: 10.1210/endocr/bqz011
Abstract: Hyperandrogenism is considered as one of the most important characteristics of polycystic ovary syndrome (PCOS) which affects more than 10% percent of females in reproductive age and is a common cause of infertility. In addition… read more here.
Keywords: offspring mice; testosterone; excess; female offspring ... See more keywords