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   Articles with "offspring rats" as a keyword



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Insulin-like Growth Factor 1 Mediates Adrenal Development Dysfunction in Offspring Rats Induced by Prenatal Food Restriction.

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recommendations! Published in 2017 at "Archives of medical research"

DOI: 10.1016/j.arcmed.2017.11.013

Abstract: BACKGROUND Our previous study demonstrated that prenatal food restriction (PFR) could induce the dysfunction of the hypothalamic-pituitary-adrenal axis and glucocorticoid-related glucose and lipid metabolic alterations in adult offspring rats. AIM OF THE STUDY To investigate… read more here.

Keywords: igf1 signaling; dysfunction; prenatal food; offspring rats ... See more keywords
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Prenatal exposure to valproic acid is associated with altered neurocognitive function and neurogenesis in the dentate gyrus of male offspring rats

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recommendations! Published in 2019 at "Brain Research"

DOI: 10.1016/j.brainres.2019.146403

Abstract: In pregnant women with epilepsy, it is imperative to balance the safety of the mother and the potential teratogenicity of anticonvulsants, which could cause impairments such as intellectual disability and cleft lip. In this study,… read more here.

Keywords: neurogenesis; dentate gyrus; valproic acid; offspring rats ... See more keywords
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Effect of waterpipe tobacco smoke exposure during lactation on learning and memory of offspring rats: Role of oxidative stress.

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recommendations! Published in 2019 at "Life sciences"

DOI: 10.1016/j.lfs.2019.04.049

Abstract: AIMS The prevalence of waterpipe tobacco smoking is increasing among breastfeeding women. Herein, the effect of maternal waterpipe tobacco smoke (WTS) exposure during lactation on learning and memory of adult offspring rats was examined. MAIN… read more here.

Keywords: memory; exposure; offspring rats; waterpipe tobacco ... See more keywords

Facilitated AMPAR endocytosis causally contributes to the maternal sleep deprivation-induced impairments of synaptic plasticity and cognition in the offspring rats

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recommendations! Published in 2018 at "Neuropharmacology"

DOI: 10.1016/j.neuropharm.2018.01.030

Abstract: ABSTRACT Maternal sleep deprivation (MSD) has been suggested to be associated with increased frequency of neurodevelopmental disorders in offspring in both humans and animal models. However, the underlying cellular and molecular mechanism is still unclear.… read more here.

Keywords: sleep deprivation; ampar endocytosis; offspring rats; maternal sleep ... See more keywords
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Prenatal dexamethasone exposure-induced a gender-difference and sustainable multi-organ damage in offspring rats via serum metabolic profile analysis.

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recommendations! Published in 2019 at "Toxicology letters"

DOI: 10.1016/j.toxlet.2019.09.007

Abstract: Prenatal dexamethasone exposure (PDE) induces developmental toxicities of multiple organs in offspring, but its serum metabolic profile changes before and after birth are unclear. Here, we employed a LC-MS-based metabolomic approach to detect serum metabolites… read more here.

Keywords: serum; offspring rats; metabolic profile; multi organ ... See more keywords
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Inducible factors and interaction of pulmonary fibrosis induced by prenatal dexamethasone exposure in offspring rats.

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recommendations! Published in 2022 at "Toxicology letters"

DOI: 10.1016/j.toxlet.2022.02.001

Abstract: This study aimed to investigate the correlation between prenatal dexamethasone exposure (PDE) and susceptibility to pulmonary fibrosis in offspring. Healthy female Wistar rats were given dexamethasone (0.2 mg/kg.d) or an equal volume of normal saline… read more here.

Keywords: female rats; offspring rats; pulmonary fibrosis; treatment ... See more keywords
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Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams.

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recommendations! Published in 2018 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.7b05418

Abstract: The growth-promoting action of betaine involves activation of GH/IGF-1 signaling, yet it remains unclear whether insulin-like growth factor 2 (IGF2), an imprinting gene, is affected by maternal dietary betaine supplementation. In this study, F1 offspring… read more here.

Keywords: imprinting control; hepatic igf2; offspring rats; betaine ... See more keywords
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Maternal restraint stress during pregnancy negatively affects behaviors and antioxidant capacity of offspring rats (Rattus norvegicus)

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recommendations! Published in 2018 at "Canadian Journal of Zoology"

DOI: 10.1139/cjz-2017-0264

Abstract: This study evaluated the effect of maternal restraint stress during the gestation period on behaviors, biochemical parameters, and antioxidant capacities of offspring rats (Rattus norvegicus (Berkenhout,1769)) at weaning age. Behaviors, plasma biochemical indices, and antioxidant… read more here.

Keywords: maternal restraint; rattus norvegicus; rats rattus; offspring rats ... See more keywords
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The effects of letrozole-induced maternal hyperandrogenism on sexual behaviors, testicular histology, and serum biochemical traits in male offspring rats: An experimental study

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recommendations! Published in 2023 at "International Journal of Reproductive Biomedicine"

DOI: 10.18502/ijrm.v21i1.12669

Abstract: Abstract Background Intrauterine endocrine abnormalities have profound effects on the development of physiological disorders. Objective This study aimed to assess the effects of in utero exposure to letrozole (an aromatase inhibitor) and its late consequences… read more here.

Keywords: male offspring; sexual behaviors; offspring rats; serum biochemical ... See more keywords
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Effects of RhoA on depression-like behavior in prenatally stressed offspring rats

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recommendations! Published in 2022 at "Behavioural Brain Research"

DOI: 10.2139/ssrn.4078735

Abstract: Depression is a common mental disease that can lead to suicide when severe. Exposure to prenatal stress (PS) can lead to depression-like behavior in offspring, but the mechanism is unclear. RhoA (Ras homology family member… read more here.

Keywords: depression; rhoa; offspring rats; like behavior ... See more keywords
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The influence of palatable high-energy diet in diet-induced obesity pregnant rats on offspring oxidative stress in liver.

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recommendations! Published in 2018 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_201804_14841

Abstract: OBJECTIVE We established an animal model of diet-induced obesity pregnant rats and their offsprings, and explored the effect of high-energy feeding on oxidative stress in filial rat liver, as well as the underlying mechanism. MATERIALS… read more here.

Keywords: control group; group; phed group; offspring rats ... See more keywords