Reconstructing an Inducible Homologous Recombination System in Ogataea Polymorpha
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DOI: 10.1002/biot.70040
Abstract: Ogataea polymorpha is a promising host for industrial production due to its broad substrate spectrum, thermotolerance, and high‐density fermentation capability. While recombination machinery engineering has improved genome editing via homologous recombination (HR), constitutive expression of… read more here.
Keywords: recombination; system; reconstructing inducible; homologous recombination ... See more keywords
Development of new dominant selectable markers for the nonconventional yeasts Ogataea polymorpha and Candida famata
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DOI: 10.1002/yea.3467
Abstract: Nonconventional yeast Candida famata and Ogataea polymorpha are interesting organisms for basic and applied studies. O. polymorpha is methylotrophic thermotolerant yeast capable of xylose alcoholic fermentation whereas C. famata is capable of riboflavin overproduction. Still,… read more here.
Keywords: new dominant; ogataea polymorpha; famata; candida famata ... See more keywords
Characterizing methanol metabolism-related promoters for metabolic engineering of Ogataea polymorpha.
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DOI: 10.1007/s00253-021-11665-5
Abstract: Promoters play an important role in regulating gene expression, and construction of microbial cell factories requires multiple promoters for balancing the metabolic pathways. However, there are only a limited number of characterized promoters for gene… read more here.
Keywords: methanol metabolism; polymorpha; ogataea polymorpha; gene expression ... See more keywords
Regulation of mating type switching by the mating type genes and RME1 in Ogataea polymorpha
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DOI: 10.1038/s41598-017-16284-7
Abstract: Saccharomyces cerevisiae and its closely related yeasts undergo mating type switching by replacing DNA sequences at the active mating type locus (MAT) with one of two silent mating type cassettes. Recently, a novel mode of… read more here.
Keywords: ogataea polymorpha; mating type; type genes; type ... See more keywords
Positive selection of efficient ethanol producers from xylose at 45 °C in the yeast Ogataea polymorpha
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DOI: 10.1038/s41598-025-12204-2
Abstract: This research presents a method for the positive selection of mutants with improved xylose and L-arabinose fermentation in the thermotolerant, naturally xylose-utilizing yeast Ogataea polymorpha which is based on isolation of the mutants growing on… read more here.
Keywords: yeast ogataea; polymorpha; fermentation; ogataea polymorpha ... See more keywords
Random Transfer of Ogataea polymorpha Genes into Saccharomyces cerevisiae Reveals a Complex Background of Heat Tolerance
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DOI: 10.3390/jof7040302
Abstract: Horizontal gene transfer, a process through which an organism acquires genes from other organisms, is a rare evolutionary event in yeasts. Artificial random gene transfer can emerge as a valuable tool in yeast bioengineering to… read more here.
Keywords: ogataea polymorpha; heat tolerance; polymorpha genes; transfer ... See more keywords
Polo-like kinase Cdc5 regulates Spc72 recruitment to spindle pole body in the methylotrophic yeast Ogataea polymorpha
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DOI: 10.7554/elife.24340
Abstract: Cytoplasmic microtubules (cMT) control mitotic spindle positioning in many organisms, and are therefore pivotal for successful cell division. Despite its importance, the temporal control of cMT formation remains poorly understood. Here we show that unlike… read more here.
Keywords: ogataea polymorpha; like kinase; recruitment; polo like ... See more keywords