Optical Genome Mapping: A Promising New Tool to Assess Genomic Complexity in Chronic Lymphocytic Leukemia (CLL)
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14143376
Abstract: Simple Summary Genome complexity, detected by chromosome banding analysis or chromosomal microarray analysis, is a poor prognostic factor for chronic lymphocytic leukemia (CLL). Herein, we aimed to assess the performance of optical genome mapping (OGM)… read more here.
Keywords: lymphocytic leukemia; chronic lymphocytic; genomic complexity; cll ... See more keywords
Optical Genome Mapping as an Alternative to FISH-Based Cytogenetic Assessment in Chronic Lymphocytic Leukemia
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15041294
Abstract: Simple Summary In many countries, the standard-of-care cytogenetic analysis of chronic lymphocytic leukemia (CLL) is based on the fluorescence in situ hybridization (FISH) technique. This offers only a very targeted view of genomic alterations. Recent… read more here.
Keywords: lymphocytic leukemia; genome wide; analysis; chronic lymphocytic ... See more keywords
The Application of Optical Genome Mapping (OGM) in Severe Short Stature Caused by Duplication of 15q14q21.3
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14051016
Abstract: (1) Background: Optical genome mapping (OGM) is a novel approach to identifying genomic structural variations with high accuracy and resolution. We report a proband with severe short stature caused by 46, XY, der (16) ins… read more here.
Keywords: short stature; duplication 15q14q21; ogm; duplication ... See more keywords