Regulation of GATA-1-Controlled Genes By O-Glcnacylation in Erythroid Cells
Sign Up to like & getrecommendations! Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-141429
Abstract: The role of post-translational modification (PTM) of proteins in regulating developmental and differentiation processes is understudied, but recently we established that O-GlcNAcylation regulates erythropoiesis. O-GlcNAc regulates numerous cellular functions including stress response, transcription, and cell… read more here.
Keywords: ogt oga; erythropoiesis; globin; gata ... See more keywords
Blocking ATM Attenuates SKOV3 Cell Proliferation and Migration by Disturbing OGT/OGA Expression via hsa-miR-542-5p
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.839508
Abstract: Blocking ataxia telangiectasia mutated (ATM), a crucial player in DNA repair responses, has been proposed as a promising strategy in anti-cancer therapy. Most previous studies have focused on DNA damage response-related pathways after administration of… read more here.
Keywords: cell; mir 542; ogt oga; expression ... See more keywords
The Emerging Roles of Protein Interactions with O-GlcNAc Cycling Enzymes in Cancer
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DOI: 10.3390/cancers14205135
Abstract: Simple Summary Dynamic O-GlcNAc modification regulates the functions of proteins in a broad range of cellular processes. Dysregulation of the sole enzymes responsible for O-GlcNAc cycling, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA), and the associated… read more here.
Keywords: ogt oga; glcnac cycling; emerging roles; protein interactions ... See more keywords