7α-Hydroxycholesterol induces monocyte/macrophage cell expression of interleukin-8 via C5a receptor
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DOI: 10.1371/journal.pone.0173749
Abstract: We investigated effects of 7-oxygenated cholesterol derivatives present in atherosclerotic lesions, 7α-hydroxycholesterol (7αOHChol), 7β-hydroxycholesterol (7βOHChol), and 7-ketocholesterol (7K), on IL-8 expression. Transcript levels of IL-8 and secretion of its corresponding gene product by monocytes/macrophages were… read more here.
Keywords: monocyte macrophage; expression; c5a receptor; ohchol ... See more keywords