IGF-1R Regulates the Extracellular Level of Active MMP-2, Pathological Neovascularization, and Functionality in Retinas of OIR Mouse Model
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DOI: 10.1007/s12035-017-0386-9
Abstract: In ischemic proliferative diseases such as retinopathies, persistent hypoxia leads to the release of numerous neovascular factors that participate in the formation of abnormal vessels and eventually cause blindness. The upregulation and activation of metalloproteinases… read more here.
Keywords: active mmp; oir mouse; igf; model ... See more keywords