Integrated OPECT and Smartphone Colorimetry Dual‐Mode Detection of Okadaic Acid Based on Ce‐MOF Modified MXene@SnO2 Z‐Scheme Heterostructure
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202415174
Abstract: The organic photoelectrochemical transistor (OPECT) biosensing relies solely on a singular signal readout inherently, which restrains the precision and dependability nestled within pertinent biological measurements. Herein, a high‐precision magnetic assisted OPECT and smartphone colorimetric (SCL)… read more here.
Keywords: detection; opect smartphone; dual mode; colorimetry ... See more keywords
Okadaic acid promotes epithelial‐mesenchymal transition of hepatocellular carcinoma cells by inhibiting protein phosphatase 2A
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29629
Abstract: As a specific inhibitor of serine/threonine protein phosphatases, okadaic acid (OA) has been found to be a tumor promoter. However, whether OA plays a role in metastasis of hepatocellular carcinoma (HCC) has not been well… read more here.
Keywords: hepatocellular carcinoma; mesenchymal transition; cells inhibiting; epithelial mesenchymal ... See more keywords
Changes in colonic microbiotas in rat after long-term exposure to low dose of okadaic acid.
Sign Up to like & getrecommendations! Published in 2020 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2020.126874
Abstract: Okadaic acid (OA), one of the most important phycotoxins, is widely distributed around the world, concerning diarrheic shellfish poisoning (DSP), and even colorectal cancer. Here, we found that long-term exposure of OA at a low… read more here.
Keywords: colonic microbiotas; low dose; term exposure; long term ... See more keywords
Variability and profiles of lipophilic toxins in bivalves from Great Britain during five and a half years of monitoring: Okadaic acid, dinophysis toxins and pectenotoxins.
Sign Up to like & getrecommendations! Published in 2018 at "Harmful algae"
DOI: 10.1016/j.hal.2018.05.011
Abstract: Official control biotoxin testing of bivalve molluscs from Great Britain has been conducted by Cefas for over a decade. Reflecting the changes in legislation, bioassays were gradually replaced by analytical methods, firstly for analysis of… read more here.
Keywords: great britain; lipophilic toxins; dinophysis; years monitoring ... See more keywords
Sorption of okadaic acid lipophilic toxin onto plastics in seawater.
Sign Up to like & getrecommendations! Published in 2020 at "Marine pollution bulletin"
DOI: 10.1016/j.marpolbul.2020.111322
Abstract: The present study tested under laboratorial conditions the sorption of okadaic acid (OA), a lipophilic toxin produced by marine phytoplankton, onto 6-mm plastic circular fragments. Fragments (4 g L-1) of polyethylene terephthalate (PET), polypropylene (PP), expanded polystyrene… read more here.
Keywords: acid lipophilic; lipophilic toxin; sorption okadaic; sorption ... See more keywords
The GSK3β inhibitor, TDZD-8, rescues cognition in a zebrafish model of okadaic acid-induced Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2019 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2018.10.022
Abstract: &NA; Currently, no treatments exist that are able to directly treat against Alzheimer's disease (AD), and we are facing an inevitable increase in the near future of the amount of patients who will suffer from… read more here.
Keywords: inhibitor; group; tdzd; model ... See more keywords
Sublethal doses of dinophysistoxin‐1 and okadaic acid stimulate secretion of inflammatory factors on innate immune cells: Negative health consequences
Sign Up to like & getrecommendations! Published in 2017 at "Toxicon"
DOI: 10.1016/j.toxicon.2016.12.005
Abstract: ABSTRACT One of the proposed mechanisms to explain why Diarrhetic Shellfish Poison (DSP) toxins are tumor promoters is founded on the capacity of these toxins to increase TNF‐&agr; secretion. Although macrophages are the principal cells… read more here.
Keywords: stimulate secretion; secretion; sublethal doses; inflammatory factors ... See more keywords
Antibody-free and selective detection of okadaic acid using an affinity peptide-based indirect assay.
Sign Up to like & getrecommendations! Published in 2023 at "Food chemistry"
DOI: 10.2139/ssrn.4375844
Abstract: Okadaic acid (OA) is a type of marine biotoxin produced by some species of dinoflagellates in marine environments. Consumption of shellfish contaminated with OA can cause diarrhetic shellfish poisoning (DSP) in humans with symptoms that… read more here.
Keywords: peptide based; okadaic acid; detection; affinity peptide ... See more keywords
A Sensitive Fluorescence Polarization Immunoassay for the Rapid Detection of Okadaic Acid in Environmental Waters
Sign Up to like & getrecommendations! Published in 2023 at "Biosensors"
DOI: 10.3390/bios13040477
Abstract: In this study, a homogeneous fluorescence polarization immunoassay (FPIA) for the detection of hazardous aquatic toxin okadaic acid (OA) contaminating environmental waters was for the first time developed. A conjugate of the analyte with a… read more here.
Keywords: okadaic acid; detection; fluorescence; polarization immunoassay ... See more keywords
Harnessing in Silico Design for Electrochemical Aptasensor Optimization: Detection of Okadaic Acid (OA)
Sign Up to like & getrecommendations! Published in 2025 at "Biosensors"
DOI: 10.3390/bios15100665
Abstract: The urgent need for advanced analytical tools for environmental monitoring and food safety drives the development of novel biosensing approaches and solutions. A computationally driven workflow for the development of a rapid electrochemical aptasensor for… read more here.
Keywords: detection; electrochemical aptasensor; okadaic acid; design ... See more keywords
Establishing Detection Methods for Okadaic Acid Aptamer–Target Interactions: Insights from Computational and Experimental Approaches
Sign Up to like & getrecommendations! Published in 2025 at "Foods"
DOI: 10.3390/foods14050854
Abstract: The binding interactions between okadaic acid (OA) aptamers and OA molecules are crucial for developing effective detection methods. This study aims to identify the recognition site and establish a reliable detection protocol through computational simulations… read more here.
Keywords: detection; aptamer target; target interactions; detection methods ... See more keywords