Processing of eukaryotic Okazaki fragments by redundant nucleases can be uncoupled from ongoing DNA replication in vivo
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DOI: 10.1093/nar/gky1242
Abstract: Abstract Prior to ligation, each Okazaki fragment synthesized on the lagging strand in eukaryotes must be nucleolytically processed. Nuclease cleavage takes place in the context of 5′ flap structures generated via strand-displacement synthesis by DNA… read more here.
Keywords: lagging strand; synthesis; okazaki fragments; dna ... See more keywords