Efficacy and Safety of Olanzapine in Children Receiving Highly Emetogenic Chemotherapy: A Randomized, Double-blind Placebo-controlled Phase 3 Trial
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000002408
Abstract: Background: In this trial, we evaluated the safety and efficacy of olanzapine in children receiving highly emetogenic chemotherapy. Materials and Methods: In this study, patients aged 3 to 18 years were randomly assigned to either… read more here.
Keywords: olanzapine group; control; highly emetogenic; group ... See more keywords
Clinical Observation of Gene Polymorphism of Olanzapine or Aprepitant in Prevention of CINV
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacogenomics and Personalized Medicine"
DOI: 10.2147/pgpm.s317229
Abstract: Objective The present study aims to investigate the correlation between the gene polymorphisms of the multidrug resistance protein 1 (ABCB1), the intron region of transcriptional factor (GTF2E1) and catechol-O-methyltransferase (COMT), dopamine receptor (DRD2), and the… read more here.
Keywords: cinv; gene; olanzapine aprepitant; olanzapine group ... See more keywords