Metformin attenuates antipsychotic-induced metabolic dysfunctions in MK801-induced schizophrenia-like rats
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DOI: 10.1007/s00213-020-05524-w
Abstract: Rationale Second-generation antipsychotics are the first-line medications prescribed for schizophrenic patients; however, some of them, such as olanzapine and risperidone, may induce metabolic dysfunctions during short-term treatment. Metformin is an effective adjuvant that attenuates antipsychotic-induced… read more here.
Keywords: schizophrenia like; mk801 induced; olanzapine risperidone; metabolic dysfunctions ... See more keywords
A Double-Blind, Placebo-Controlled Trial of Bupropion Add-on to Olanzapine or Risperidone in Overweight Individuals With Schizophrenia
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DOI: 10.1097/jcp.0000000000001481
Abstract: Abstract Background Weight gain due to antipsychotics is a challenging clinical problem because, to date, no effective pharmacological strategies have been found. Bupropion is often used in people with schizophrenia for smoking cessation and is… read more here.
Keywords: olanzapine risperidone; overweight individuals; placebo; double blind ... See more keywords