Olaparib and temozolomide in desmoplastic small round cell tumors: a promising combination in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-020-03211-z
Abstract: Purpose Desmoplastic small round cell tumors (DSRCTs) are highly malignant and very rare soft tissue sarcomas with a high unmet need for new therapeutic options. Therefore, we examined poly(ADP-ribose) polymerase 1 (PARP1) and Schlafen-11 (SLFN11)… read more here.
Keywords: combination; olaparib tmz; combination treatment; desmoplastic small ... See more keywords
Combination Olaparib and Temozolomide for the Treatment of Glioma
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DOI: 10.1212/wnl.0000000000201203
Abstract: Background and Objectives To report the tolerability and efficacy of olaparib with temozolomide (TMZ) for glioma. Methods Single-center retrospective series of patients with glioma treated with olaparib/TMZ from September 2018 to December 2021. Results Twenty… read more here.
Keywords: idh mutant; glioma; olaparib temozolomide; olaparib tmz ... See more keywords