Leishmania spp. in a cutaneous histiocytoma of an old dog
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.24839
Abstract: A 10-year-old male Italian Volpino crossbreed dog was referred for a second opinion for not-responsive anemia. The dog had a history of travel across Europe, including Spain. A month before, the dog was visited in… read more here.
Keywords: spp cutaneous; histiocytoma old; leishmania spp; cutaneous histiocytoma ... See more keywords
Old dog, new tricks: Influenza a virus NS1 and in vitro fibrillogenesis.
Sign Up to like & getrecommendations! Published in 2021 at "Biochimie"
DOI: 10.1016/j.biochi.2021.07.005
Abstract: The influenza NS1 protein is involved in suppression of the host immune response. Recently, there is growing evidence that prion-like protein aggregation plays an important role in cellular signaling and immune responses. In this work,… read more here.
Keywords: dog new; new tricks; tricks influenza; form ... See more keywords
Teaching an old dog new tricks: repurposing β-lactams.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in pharmacological sciences"
DOI: 10.1016/j.tips.2021.06.003
Abstract: Recently, Martelli and colleagues reported on the structural and functional characterization of new antimycobacterials based on N-thio-β-lactams. Surprisingly, the inhibitory mechanism follows a path unexpected for β-lactams, providing an alternative route to defeat drug-resistant strains… read more here.
Keywords: repurposing lactams; dog new; new tricks; tricks repurposing ... See more keywords
OLD DOG, NEW TRICK: NOVEL CT-DERIVED PARAMETER IS ASSOCIATED WITH LOW CARDIAC INDEX IN ACUTE PULMONARY EMBOLISM
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(20)32900-4
Abstract: Acute pulmonary embolism (PE) has variable outcomes. Current risk stratification models lack the positive predictive value to identify highest risk patients. We hypothesize that Hounsfield unit (HU) gradient is associated with transit time of IV… read more here.
Keywords: new trick; pulmonary embolism; dog new; acute pulmonary ... See more keywords
Micrografting: an old dog plays new tricks in obligate plant pathogens.
Sign Up to like & getrecommendations! Published in 2022 at "Plant disease"
DOI: 10.1094/pdis-03-22-0475-fe
Abstract: Micrografting, which was developed almost 50 years ago, has long been used for virus eradication, micropropagation, regeneration, rejuvenation and graft compatibility. Recently, micrografting has been used for studies of long-distance trafficking and signaling of molecules… read more here.
Keywords: dog plays; obligate plant; micrografting old; plant pathogens ... See more keywords
Gamma‐Glutamyl Transferase (γ‐GT) – an old dog with new tricks?
Sign Up to like & getrecommendations! Published in 2021 at "Liver International"
DOI: 10.1111/liv.15099
Abstract: Gamma‐Glutamyl Transferase (γGT) is a key transferase involved in the transpeptidation of functional gamma‐glutamyl groups to various receptor moieties. It performs important roles in antioxidant defence mechanisms, particularly glutathione recycling, xenobiotic metabolism, but analogously may… read more here.
Keywords: transferase old; old dog; glutamyl transferase; dog new ... See more keywords
New Tricks for an Old Dog: Biased GPCR Agonism of an M4 Muscarinic Acetylcholine Receptor Antagonist in Airway Smooth Muscle Cells
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Respiratory Cell and Molecular Biology"
DOI: 10.1165/rcmb.2022-0335ed
Abstract: ligands, the expectation is that they will only trigger G-protein–independent pathways that promote antiremodeling and bronchorelaxant actions via b -arrestin pathways that are distinct from those driving bronchial hyperresponsiveness. The study by Tompkins provides strong… read more here.
Keywords: biased gpcr; tricks old; dog biased; old dog ... See more keywords
How Old Is My Dog? Identification of Rational Age Groupings in Pet Dogs Based Upon Normative Age-Linked Processes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2021.643085
Abstract: Behavioral development is a lifelong process where cognitive traits such as learning and memory may be expected to take quadratic or linear trajectories. It is common practice for operational purposes to reduce study subjects into… read more here.
Keywords: age; comparison studies; dog identification; old dog ... See more keywords