Older and younger patients treated with immune checkpoint inhibitors have similar outcomes in real-life setting.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of cancer"
DOI: 10.1016/j.ejca.2019.08.027
Abstract: BACKGROUND Age-related immune dysfunction might impair the efficacy of immune checkpoint inhibitors (ICIs) in older patients. We aimed to evaluate the impact of age on clinical outcomes and tolerance of ICIs in a real-life setting.… read more here.
Keywords: immune checkpoint; checkpoint inhibitors; younger patients; older younger ... See more keywords
Ageism towards older and younger people in the wake of the COVID-19 outbreak
Sign Up to like & getrecommendations! Published in 2021 at "Maturitas"
DOI: 10.1016/j.maturitas.2021.11.002
Abstract: Objectives The COVID-19 pandemic has provided a rich environment for ageist attitudes towards both older and younger people. However, publications on ageism during the outbreak have been mostly non-empirical and have concentrated on ageist beliefs… read more here.
Keywords: older people; ageism; towards older; younger people ... See more keywords
Minimally Invasive Transforaminal Lumbar Interbody Fusion: A Comparison Study Based on End Plate Subsidence and Cystic Change in Individuals Older and Younger than 65 Years.
Sign Up to like & getrecommendations! Published in 2017 at "World neurosurgery"
DOI: 10.1016/j.wneu.2017.06.136
Abstract: OBJECTIVE To compare the outcomes between patients older and younger than 65 years who underwent single-level minimally invasive transforaminal interbody fusion (MI-TLIF) surgery. METHODS This study is a retrospective analysis of 76 patients who underwent… read more here.
Keywords: younger years; group; rate; older younger ... See more keywords
Differences in appetite-related hormone concentrations between older and younger adults: A systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the Nutrition Society"
DOI: 10.1017/s0029665118001647
Abstract: Unintentional weight loss is common in older adults, partly due to a loss of appetite termed ‘the anorexia of ageing’. This is associated with adverse health outcomes including reduced functional capacity and increased mortality rates,… read more here.
Keywords: analysis; younger adults; older younger; concentrations older ... See more keywords
How is personality related to well-being in older and younger adults? The role of psychological flexibility
Sign Up to like & getrecommendations! Published in 2018 at "International Psychogeriatrics"
DOI: 10.1017/s1041610218001904
Abstract: ABSTRACT Objectives: Personality is known to be a reliable predictor of well-being. However, it is rather difficult to influence the personality of individuals in order to improve their well-being. Therefore, it is important to examine… read more here.
Keywords: psychological flexibility; younger adults; flexibility; indirect effects ... See more keywords
Effects of blood pressure-lowering treatment on cardiovascular outcomes and mortality: 13 – benefits and adverse events in older and younger patients with hypertension overview, meta-analyses and meta-regression analyses of randomized trials
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/hjh.0000000000001787
Abstract: Background: There is overwhelming evidence that blood pressure (BP)-lowering treatment can reduce cardiovascular outcomes also in the elderly, but some important aspects influencing medical practice are controversial as sufficient evidence has not been provided by… read more here.
Keywords: lowering treatment; age; treatment; cardiovascular outcomes ... See more keywords
Extreme duration exercise affects old and younger men differently.
Sign Up to like & getrecommendations! Published in 2022 at "Acta physiologica"
DOI: 10.1111/apha.13816
Abstract: AIM & METHODS Extreme endurance exercise provides a valuable research model for understanding the adaptive metabolic response of older and younger individuals to intense physical activity. Here, we compare a wide range of metabolic and… read more here.
Keywords: response; extreme duration; older younger; extreme endurance ... See more keywords
Older, Younger, or More Similar? The Use of Age as a Voting Heuristic*
Sign Up to like & getrecommendations! Published in 2019 at "Social Science Quarterly"
DOI: 10.1111/ssqu.12604
Abstract: Objective The descriptive representation literature has found that individuals prefer to vote for candidates who share similar characteristics as themselves. However, the relationship between the age of a voter and the age of a candidate… read more here.
Keywords: older younger; younger similar; use age; voting heuristic ... See more keywords
Exogenous Caffeine Ingestion Does Not Increase Plantarflexor Torque in Older or Younger Men.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of aging and physical activity"
DOI: 10.1123/japa.2022-0074
Abstract: Aging is associated with neurodegeneration and a loss of muscle function, especially in lower-limb muscles. While caffeine may augment muscle force generation through multiple effects on the central nervous system, no studies have yet compared… read more here.
Keywords: plantarflexor torque; older younger; caffeine; younger men ... See more keywords
Factors associated with the uptake of seasonal influenza vaccination in older and younger adults: a large, population-based survey in Beijing, China
Sign Up to like & getrecommendations! Published in 2017 at "BMJ Open"
DOI: 10.1136/bmjopen-2017-017459
Abstract: Objectives The present study aimed to estimate the influenza vaccination coverage rate in Beijing, China, and identify its determinants in older and younger adults. Methods A survey was conducted among Chinese adults using a self-administered,… read more here.
Keywords: influenza; younger adults; older younger; influenza vaccination ... See more keywords
Thermoregulatory and Renal Responses to Simulated Heatwaves in Younger and Older Adults
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5732551
Abstract: The frequency, intensity, and duration of heat waves are projected to increase in the coming decades. Older adults have impaired heat-dissipating capabilities and are at a greater risk for heat-related morbidity and mortality. Many hospitalizations… read more here.
Keywords: older adults; older younger; temperature; physiology ... See more keywords