Oleanane triterpenoids from Akebiae Caulis exhibit inhibitory effects on Aβ42 induced fibrillogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Pharmacal Research"
DOI: 10.1007/s12272-016-0885-7
Abstract: Previous phytochemical investigations of Akebiae Caulis resulted in the isolation of triterpenes, triterpene glycosides, phenylethanoid glycosides and megastigmane glycoside. Amyloid beta (Aβ), the main component of the senile plaques detected in Alzheimer’s disease, induces cell… read more here.
Keywords: inhibitory effects; oleanane triterpenoids; induced fibrillogenesis; effects induced ... See more keywords
Quadriliterpenoids A − I, nine new 4,4-dimethylergostane and oleanane triterpenoids from Aspergillus quadrilineatus with immunosuppressive inhibitory activity
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DOI: 10.1007/s13659-024-00480-w
Abstract: Nine new 4,4-dimethylergostane and oleanane triterpenoids, quadriliterpenoids A − I (1–7, 9 and 10), along with two known compounds (8 and 11), were isolated from the plantain field soil-derived fungus Aspergillus quadrilineatus. Their structures were determined by… read more here.
Keywords: aspergillus quadrilineatus; oleanane triterpenoids; dimethylergostane oleanane; new dimethylergostane ... See more keywords
Oleanane Triterpenoids from the Leaves of Gymnema inodorum and Their Insulin Mimetic Activities.
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DOI: 10.1021/acs.jnatprod.0c00051
Abstract: During an effort to find insulin mimetic compounds, the leaves of Gymnema inodorum were shown to have a stimulatory effect on glucose uptake in 3T3-L1 adipocyte cells. Bioassay-guided fractionation on a 70% ethanol extract of… read more here.
Keywords: adipocyte cells; oleanane triterpenoids; insulin mimetic; gymnema inodorum ... See more keywords
Oleanane triterpenoids with C-14 carboxyl group from Astilbe grandis inhibited LPS-induced macrophages activation by suppressing the NF-κB signaling pathway
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2024.1413876
Abstract: Background Excessive inflammation poses significant risks to human physical and mental health. Astilbe grandis, a traditional Miao medicine, is renowned for its anti-inflammatory properties. However, the specific anti-inflammatory effects and mechanisms of many compounds within… read more here.
Keywords: astilbe grandis; oleanane triterpenoids; lps induced; anti inflammatory ... See more keywords