Transcriptome analysis of Panax zingiberensis identifies genes encoding oleanolic acid glucuronosyltransferase involved in the biosynthesis of oleanane-type ginsenosides
Sign Up to like & getrecommendations! Published in 2018 at "Planta"
DOI: 10.1007/s00425-018-2995-6
Abstract: Main conclusionOleanolic acid glucuronosyltransferase (OAGT) genes synthesizing the direct precursor of oleanane-type ginsenosides were discovered. The four recombinant proteins of OAGT were able to transfer glucuronic acid at C-3 of oleanolic acid that yields oleanolic… read more here.
Keywords: oleanane type; oleanolic acid; zingiberensis; type ginsenosides ... See more keywords
Phytochemical profile of Centevita®, a Centella asiatica leaves extract, and isolation of a new oleanane-type saponin.
Sign Up to like & getrecommendations! Published in 2022 at "Fitoterapia"
DOI: 10.1016/j.fitote.2022.105163
Abstract: Centella asiatica is a popular medicinal plant and several phytotherapic products in the market include its extracts as active constituents. A LC-MS guided phytochemical investigation on the commercial C. asiatica leaves extract named Centevita® allowed… read more here.
Keywords: asiatica leaves; centella asiatica; oleanane type; leaves extract ... See more keywords
Oleanane-type glycosides isolated from the trunk barks of the central African tree Millettia laurentii.
Sign Up to like & getrecommendations! Published in 2022 at "Fitoterapia"
DOI: 10.1016/j.fitote.2022.105193
Abstract: Seven previously undescribed oleanane-type glycosides were isolated from the trunk barks of a Central African tree named Millettia laurentii De Wild (Fabaceae). After the extraction from the barks, the isolation and purification of these compounds… read more here.
Keywords: glucuronopyranosylechinocystic acid; acid apiofuranosyl; galactopyranosyl; oleanane type ... See more keywords
Anti-inflammatory Oleanane-Type Triterpenoids Produced by Nonomuraea sp. MYH522 through Microbial Transformation.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c09062
Abstract: Eleven oleanane-type triterpenoids named soyasapogenols B1-B11 have been obtained unexpectedly from a marine actinomycete Nonomuraea sp. MYH522. Their structures have been determined by extensive analysis of spectroscopic experiments and X-ray crystallographic data. Soyasapogenols B1-B11 exhibit… read more here.
Keywords: oleanane type; anti inflammatory; type triterpenoids; nonomuraea myh522 ... See more keywords
Discovery, Preliminary Structure-Activity Relationship, and Evaluation of Oleanane-Type Saponins from Pulsatilla chinensis for the Treatment of Ulcerative Colitis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.3c00112
Abstract: To discover ulcerative colitis (UC) treatment agents, 28 oleanane-type triterpenoid saponins (1-28) including three new saponins, pulsatillosides P-R (1-3), were isolated from Pulsatilla chinensis. The isolated saponins could observably ameliorate UC by improving the intestinal… read more here.
Keywords: oleanane type; treatment; type saponins; chinensis ... See more keywords
Flower- and Grass-like Self-Assemblies of an Oleanane-Type Triterpenoid Erythrodiol: Application in the Removal of Toxic Dye from Water
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DOI: 10.1021/acsomega.0c04291
Abstract: Erythrodiol (3β-olean-12-ene-3, 28-diol) (C30H50O2) 1 is a nanosized oleanane-type fused 6-6-6-6-6 pentacyclic triterpeneoid extractable from the dried leaves of olive (Olea europia). One step reduction of oleanolic acid extracted from Lantana camara also yields the… read more here.
Keywords: microscopy; oleanane type; self; self assemblies ... See more keywords
Biological Evaluation and Docking Studies of Synthetic Oleanane-type Triterpenoids
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DOI: 10.1021/acsomega.8b01034
Abstract: Saponins are potential wide-spectrum antitumor drugs, and copper(I) catalyzed azide–alkyne 1,3-dipolar cycloaddition is a suitable approach to synthesizing saponin-like compounds by regioselective glycosylation of the C2/C3 hydroxyl and C28 carboxylic groups of triterpene aglycones maslinic… read more here.
Keywords: evaluation docking; biological evaluation; docking studies; studies synthetic ... See more keywords
In vitro anti-inflammatory, in silico molecular docking and molecular dynamics simulation of oleanane-type triterpenes from aerial parts of Mussaenda recurvata
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DOI: 10.1039/d2ra06870b
Abstract: Bioactive-guided investigation of the aerial parts of Mussaenda recurvata Naiki, Tagane, and Yahara (Rubiaceae) led to the isolation of four triterpenes, including two new triterpenes recurvatanes A and B (1 and 2), along with two… read more here.
Keywords: molecular docking; type triterpenes; parts mussaenda; mussaenda recurvata ... See more keywords
Enzymatic glycosylation of oleanane-type triterpenoids
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Asian Natural Products Research"
DOI: 10.1080/10286020.2018.1478818
Abstract: Abstract Glycosylation is an effective approach to improve the druggability of natural products by increasing their water solubility. In this work, we report the glycosylation of oleanane-type triterpenoids by a recombinant microbial glycosyltransferase YjiC1. A… read more here.
Keywords: oleanane type; glycosylation; type triterpenoids; enzymatic glycosylation ... See more keywords
Cytotoxic 13,28 Epoxy Bridged Oleanane-Type Triterpenoid Saponins from the Roots of Ardisia crispa
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DOI: 10.3390/molecules27031061
Abstract: Ardisiacrispin D–F (1–3), three new 13,28 epoxy bridged oleanane-type triterpenoid saponins, together with four known analogues (4–7) were isolated from the roots of Ardisia crispa. The structures of 1–7 were elucidated based on 1D and… read more here.
Keywords: type triterpenoid; triterpenoid saponins; triterpenoid; oleanane type ... See more keywords
Oleanane-Type Triterpene Conjugates with 1H-1,2,3-Triazole Possessing of Fungicidal Activity
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27154928
Abstract: The triazole pesticide is an organic nitrogen-containing heterocyclic compound with a 1,2,3-Triazole ring. In order to develop a potential glucosamine-6-phosphate synthase (GlmS) inhibitor bactericide, 18 triazole-derivative compounds were synthesized efficiently. In addition, these compounds have… read more here.
Keywords: conjugates triazole; triazole possessing; type triterpene; activity ... See more keywords