LAUSR

OleD Loki as a Catalyst for Hydroxamate Glycosylation

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0 Published in 2019 at "ChemBioChem"

DOI: 10.1002/cbic.201900601

Abstract: Herein we describe the ability of the permissive glycosyltransferase (GT) OleD Loki to convert a diverse set of >15 histone deacetylase (HDAC) inhibitors (HDACis) into their corresponding hydroxamate glycosyl esters. Representative glycosyl esters were subsequently… read more here.

Keywords: hydroxamate glycosylation; catalyst hydroxamate; oled loki; loki catalyst ... See more keywords