Deciphering Pyrrolidine and Olefin Formation Mechanism in Kainic Acid Biosynthesis
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DOI: 10.1021/acscatal.0c03879
Abstract: Metalloenzyme-catalyzed cyclization involving C–H bond activation is a powerful strategy to construct molecular complexity found in natural product biosynthesis. In the isodomoic acid and kainic ac... read more here.
Keywords: deciphering pyrrolidine; biosynthesis; formation mechanism; olefin formation ... See more keywords
Mild olefin formation via bio-inspired vitamin B12 photocatalysisâ€
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Science"
DOI: 10.1039/d0sc05925k
Abstract: Dehydrohalogenation, or elimination of hydrogen-halide equivalents, remains one of the simplest methods for the installation of the biologically-important olefin functionality. However, this transformation often requires harsh, strongly-basic conditions, rare noble metals, or both, limiting its… read more here.
Keywords: formation via; mild olefin; olefin formation; vitamin b12 ... See more keywords