The hopeful anticancer role of oleuropein in breast cancer through histone deacetylase modulation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28965
Abstract: Breast cancer (BC) is one of the most common cancers among women worldwide. Genetic, epigenetic, and environmental factors play a crucial role in BC development. Because epigenetic imbalance occurs earlier than expression in carcinogenesis and… read more here.
Keywords: oleuropein; histone deacetylase; breast cancer; role ... See more keywords
Anti-inflammatory effect of oleuropein on microglia through regulation of Drp1-dependent mitochondrial fission
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2017.02.019
Abstract: Oleuropein is a primary phenolic compound found in olive leaf and Fraxinus rhynchophylla. Here, we investigated the impact of oleuropein on LPS-induced BV-2 microglial cells. Oleuropein suppressed the LPS-induced increase in pro-inflammatory mediators, such as… read more here.
Keywords: dependent mitochondrial; drp1 dependent; oleuropein; fission ... See more keywords
Olive Component Oleuropein Promotes β-Cell Insulin Secretion and Protects β-Cells from Amylin Amyloid-Induced Cytotoxicity.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry"
DOI: 10.1021/acs.biochem.7b00199
Abstract: Oleuropein, a natural product derived from olive leaves, has reported anti-diabetic functions. However, detailed molecular mechanisms for how it affects β-cell functions remain poorly understood. Here, we present evidence that oleuropein promotes glucose-stimulated insulin secretion… read more here.
Keywords: oleuropein; insulin secretion; olive component; cytotoxicity ... See more keywords
Calcium ions hyaluronan/gellan gum protective shell for delivery of oleuropein in the knee
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Polymeric Materials and Polymeric Biomaterials"
DOI: 10.1080/00914037.2020.1848831
Abstract: Abstract Oleuropein has several beneficial properties. Strong evidences of its role in preventing osteoarthritis and playing analgesic and sedative effects are gaining. Starting from that, we entrapped a vegetal bioactive matrix rich in oleuropein into… read more here.
Keywords: gellan gum; ions hyaluronan; hyaluronan gellan; oleuropein ... See more keywords
Preparation of highly purified oleuropein by combinative technology off line of HSCCC-PHPLC based on dual wavelength.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of food science"
DOI: 10.1111/1750-3841.15903
Abstract: Oleuropein is the main active substance in foods or functional foods produced from olive (Olea europaea L.) leaves. In the present study, the combinative technology off line of HSCCC-PHPLC based on dual wavelength was used… read more here.
Keywords: phplc; highly purified; oleuropein; purified oleuropein ... See more keywords
FRI0653-HPR AN OLEUROPEIN-BASED DIETARY SUPPLEMENT IMPROVES JOINT FUNCTIONALITY IN OLDER PEOPLE WITH HIGH KNEE JOINT PAIN
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-eular.3655
Abstract: OLE provides oleuropein the most prevalent phenolic component in olive leaves and has been shown to have potent anti-inflammatory and anti-oxidant effects potentially interesting for joint health (1).The aim of this study was to investigate… read more here.
Keywords: knee joint; koos score; oleuropein; pain ... See more keywords