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Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/5010741
Abstract: Alzheimer's disease is a proteinopathy characterized by accumulation of hyperphosphorylated Tau and β-amyloid. Autophagy is a physiological process by which aggregated proteins and damaged organelles are eliminated through lysosomal digestion. Autophagy deficiency has been demonstrated…
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Keywords:
alzheimer disease;
disease;
benefit oleuropein;
alzheimer patients ... See more keywords
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Published in 2018 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2018.00239
Abstract: Oleuropein aglycone, which is the major phenolic component of extra virgin olive oil, is gaining popularity and importance in scientific and public communities. This paper summarizes the structure properties, acquisition protocols, and biological activities of…
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Keywords:
biological activities;
acquisition protocols;
oleuropein aglycone;
protocols biological ... See more keywords
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3
Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15030277
Abstract: The release of monomers from the homotetrameric protein transthyretin (TTR) is the first event of a cascade, eventually leading to sporadic or familial TTR amyloidoses. Thus, ligands able to stabilize TTR and inhibit monomer release…
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Keywords:
ttr;
aglycone complex;
oleuropein aglycone;
interaction ... See more keywords