A genetic platform for functionally profiling odorant receptors in olfactory cilia ex vivo
Sign Up to like & getrecommendations! Published in 2022 at "Science Signaling"
DOI: 10.1126/scisignal.abm6112
Abstract: The molecular basis for odor perception in humans remains enigmatic because of the difficulty in studying odorant receptors (ORs) outside their native environment. Efforts toward OR expression and functional profiling have been met with limited… read more here.
Keywords: odorant receptors; platform; olfactory cilia; olfactory sensory ... See more keywords
Reversal of ciliary mechanisms of disassembly rescues olfactory dysfunction in ciliopathies
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.158736
Abstract: Ciliopathies are a class of genetic diseases resulting in cilia dysfunction in multiple organ systems, including the olfactory system. Currently, there are no available curative treatments for olfactory dysfunction and other symptoms in ciliopathies. The… read more here.
Keywords: olfactory dysfunction; olfactory cilia; reversal ciliary; dysfunction ... See more keywords