Articles with "olfactory ensheathing" as a keyword



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Olfactory ensheathing cells from the nasal mucosa and olfactory bulb have distinct membrane properties

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Published in 2019 at "Journal of Neuroscience Research"

DOI: 10.1002/jnr.24566

Abstract: Transplantation of olfactory ensheathing cells (OECs) is a potential therapy for the regeneration of damaged neurons. While they maintain tissue homeostasis in the olfactory mucosa (OM) and olfactory bulb (OB), their regenerative properties also support… read more here.

Keywords: olfactory; membrane properties; olfactory ensheathing; ensheathing cells ... See more keywords
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Comparison of the effects of two therapeutic strategies based on olfactory ensheathing cell transplantation and repetitive magnetic stimulation after spinal cord injury in female mice

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Published in 2021 at "Journal of Neuroscience Research"

DOI: 10.1002/jnr.24836

Abstract: Spinal cord injury (SCI) is a debilitating condition, which leads to a permanent loss of functions below the injury site. The events which take place after SCI are characterized by cellular death, release of inhibitory… read more here.

Keywords: sci; olfactory ensheathing; magnetic stimulation; transplantation ... See more keywords
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Isolation of Rat Olfactory Ensheathing Cells and Their Use in the Therapy of Posttraumatic Cysts of the Spinal Cord

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Published in 2018 at "Bulletin of Experimental Biology and Medicine"

DOI: 10.1007/s10517-018-4114-x

Abstract: We evaluated the efficacy of rat olfactory ensheathing cells in the therapy of experimental cysts of the spinal cord. Improvement of the motor function of the hind limbs after transplantation of the olfactory ensheathing cells… read more here.

Keywords: olfactory ensheathing; ensheathing cells; rat olfactory; spinal cord ... See more keywords
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Survival and Migration of Rat Olfactory Ensheathing Cells after Transplantation into Posttraumatic Cysts in the Spinal Cord

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Published in 2018 at "Bulletin of Experimental Biology and Medicine"

DOI: 10.1007/s10517-018-4299-z

Abstract: We studied survival of rat ensheathing cells after transplantation into experimental posttraumatic cysts. These cells were prepared according to our original protocol, labeled with intravital membrane dye PKH26, and transplanted into posttraumatic cysts of the… read more here.

Keywords: olfactory ensheathing; ensheathing cells; posttraumatic cysts; cysts spinal ... See more keywords
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Lipid Rafts from Olfactory Ensheathing Cells: Molecular Composition and Possible Roles

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Published in 2020 at "Cellular and Molecular Neurobiology"

DOI: 10.1007/s10571-020-00869-4

Abstract: Olfactory ensheathing cells (OECs) are specialized glial cells of the olfactory system, believed to play a role in the continuous production of olfactory neurons and ensheathment of their axons. Although OECs are used in therapeutic… read more here.

Keywords: olfactory ensheathing; migration; ensheathing cells; lipid rafts ... See more keywords
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Wnt-activated olfactory ensheathing cells stimulate neural stem cell proliferation and neuronal differentiation

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Published in 2020 at "Brain Research"

DOI: 10.1016/j.brainres.2020.146726

Abstract: Olfactory ensheathing cells (OECs) are special glial cells localized in olfactory system which secrete large number of neurotrophic factors and promote the migration and survival of neurons. Canonical Wnt/β-catenin signaling is activated in OECs during… read more here.

Keywords: wnt; olfactory ensheathing; proliferation; wnt activated ... See more keywords
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Neuroprotective effect of olfactory ensheathing cells co‐transfected with Nurr1 and Ngn2 in both in vitro and in vivo models of Parkinson's disease

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Published in 2018 at "Life Sciences"

DOI: 10.1016/j.lfs.2017.12.038

Abstract: Aims: The aim of the study is to evaluate the neuroprotective effects of olfactory ensheathing cells (OECs) with the overexpression of nuclear receptor‐related factor 1 (Nurr1) and neurogenin 2 (Ngn2) in experimental models of Parkinson's… read more here.

Keywords: models parkinson; olfactory ensheathing; nurr1 ngn2; ensheathing cells ... See more keywords
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Lysophosphatidic acid guides the homing of transplanted olfactory ensheathing cells to the lesion site after spinal cord injury in rats.

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Published in 2019 at "Experimental cell research"

DOI: 10.1016/j.yexcr.2019.03.023

Abstract: Olfactory ensheathing cells (OECs) are ideal candidates for cell-based therapies aimed at repairing spinal cord injury (SCI). Accurate targeting of OECs to the lesion site is critical to reconstructing the impaired nervous system. However, the… read more here.

Keywords: olfactory ensheathing; lesion site; injury; ensheathing cells ... See more keywords
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Transplantation of microencapsulated olfactory ensheathing cells inhibits the P2X2 receptor over-expressionmediated neuropathic pain in the L4–5 spinal cord segment

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Published in 2020 at "International Journal of Neuroscience"

DOI: 10.1080/00207454.2020.1713775

Abstract: Abstract Objectives The purpose of this study was to determine the effect of microencapsulated olfactory ensheathing cells (MC-OECs) transplantation on neuropathic pain (NPP) caused by sciatic nerve injury in rats, and its relationship with the… read more here.

Keywords: olfactory ensheathing; cord segment; transplantation; spinal cord ... See more keywords
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Extracellular vesicles isolated from human olfactory ensheathing cells enhance the viability of neural progenitor cells

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Published in 2020 at "Neurological Research"

DOI: 10.1080/01616412.2020.1794371

Abstract: ABSTRACT Objective Acquired neurological diseases such as severe traumatic brain or spinal cord injury (SCI) cause irreversible disability. Olfactory ensheathing cell (OEC) transplantation has been trialed as a promising SCI treatment. Extracellular vesicles (EVs), which… read more here.

Keywords: extracellular vesicles; neural progenitor; progenitor cells; olfactory ensheathing ... See more keywords
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Three-dimensional Collagen Scaffolds in Cultures of Olfactory Ensheathing Cells Used for Severed Spinal Cord Regeneration

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Published in 2022 at "In Vivo"

DOI: 10.21873/invivo.12929

Abstract: Abstract Background/Aim: The regeneration of a completely damaged spinal cord is still a challenge in modern medicine. A promising treatment method is autologous transplantation of olfactory ensheathing cells (OECs). This study aimed primarily to test… read more here.

Keywords: regeneration; collagen; ensheathing cells; olfactory ensheathing ... See more keywords