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Published in 2019 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24566
Abstract: Transplantation of olfactory ensheathing cells (OECs) is a potential therapy for the regeneration of damaged neurons. While they maintain tissue homeostasis in the olfactory mucosa (OM) and olfactory bulb (OB), their regenerative properties also support… read more here.
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Published in 2021 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24836
Abstract: Spinal cord injury (SCI) is a debilitating condition, which leads to a permanent loss of functions below the injury site. The events which take place after SCI are characterized by cellular death, release of inhibitory… read more here.
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Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-4114-x
Abstract: We evaluated the efficacy of rat olfactory ensheathing cells in the therapy of experimental cysts of the spinal cord. Improvement of the motor function of the hind limbs after transplantation of the olfactory ensheathing cells… read more here.
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Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-4299-z
Abstract: We studied survival of rat ensheathing cells after transplantation into experimental posttraumatic cysts. These cells were prepared according to our original protocol, labeled with intravital membrane dye PKH26, and transplanted into posttraumatic cysts of the… read more here.
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Published in 2020 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-020-00869-4
Abstract: Olfactory ensheathing cells (OECs) are specialized glial cells of the olfactory system, believed to play a role in the continuous production of olfactory neurons and ensheathment of their axons. Although OECs are used in therapeutic… read more here.
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Published in 2020 at "Brain Research"
DOI: 10.1016/j.brainres.2020.146726
Abstract: Olfactory ensheathing cells (OECs) are special glial cells localized in olfactory system which secrete large number of neurotrophic factors and promote the migration and survival of neurons. Canonical Wnt/β-catenin signaling is activated in OECs during… read more here.
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Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.12.038
Abstract: Aims: The aim of the study is to evaluate the neuroprotective effects of olfactory ensheathing cells (OECs) with the overexpression of nuclear receptor‐related factor 1 (Nurr1) and neurogenin 2 (Ngn2) in experimental models of Parkinson's… read more here.
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Published in 2019 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2019.03.023
Abstract: Olfactory ensheathing cells (OECs) are ideal candidates for cell-based therapies aimed at repairing spinal cord injury (SCI). Accurate targeting of OECs to the lesion site is critical to reconstructing the impaired nervous system. However, the… read more here.
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Published in 2020 at "International Journal of Neuroscience"
DOI: 10.1080/00207454.2020.1713775
Abstract: Abstract Objectives The purpose of this study was to determine the effect of microencapsulated olfactory ensheathing cells (MC-OECs) transplantation on neuropathic pain (NPP) caused by sciatic nerve injury in rats, and its relationship with the… read more here.
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Published in 2020 at "Neurological Research"
DOI: 10.1080/01616412.2020.1794371
Abstract: ABSTRACT Objective Acquired neurological diseases such as severe traumatic brain or spinal cord injury (SCI) cause irreversible disability. Olfactory ensheathing cell (OEC) transplantation has been trialed as a promising SCI treatment. Extracellular vesicles (EVs), which… read more here.
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Published in 2022 at "In Vivo"
DOI: 10.21873/invivo.12929
Abstract: Abstract Background/Aim: The regeneration of a completely damaged spinal cord is still a challenge in modern medicine. A promising treatment method is autologous transplantation of olfactory ensheathing cells (OECs). This study aimed primarily to test… read more here.