Dissecting LSD1‐Dependent Neuronal Maturation in the Olfactory Epithelium
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24259
Abstract: Neurons in the olfactory epithelium (OE) each express a single dominant olfactory receptor (OR) allele from among roughly 1,000 different OR genes. While monogenic and monoallelic OR expression has been appreciated for over two decades,… read more here.
Keywords: olfactory epithelium; maturation; expression; neuronal maturation ... See more keywords
Integrated age‐related immunohistological changes occur in human olfactory epithelium and olfactory bulb
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25325
Abstract: Olfactory epithelium (OE) is capable of lifelong regeneration due to presence of basal progenitor cells that respond to injury or neuronal loss with increased activity. However, this capability diminishes with advancing age and a decrease… read more here.
Keywords: human olfactory; olfactory bulb; olfactory; age ... See more keywords
Lifespan of mature olfactory sensory neurons varies with location in the mouse olfactory epithelium and age of the animal
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25330
Abstract: The olfactory sensory neurons (OSNs) of the olfactory epithelium (OE) exhibit a remarkable regenerative capability, which protects the population against environmental insult and enables adjustment to new odors. The lifespan of OSNs is still open… read more here.
Keywords: lifespan mature; olfactory epithelium; olfactory sensory; sensory neurons ... See more keywords
Primary Cultures of Olfactory Neurons from the Avian Olfactory Epithelium.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8600-2_19
Abstract: The culture of the olfactory epithelium has been a useful model for the study of neurogenesis since olfactory neurons regenerate continuously throughout the adult lifespan. Structurally and functionally mature olfactory neurons are generated in vitro… read more here.
Keywords: avian olfactory; primary cultures; olfactory epithelium; neurons avian ... See more keywords
Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium
Sign Up to like & getrecommendations! Published in 2019 at "Histochemistry and Cell Biology"
DOI: 10.1007/s00418-019-01785-5
Abstract: The nose is a complex organ that filters and warms breathing airflow. The nasal epithelium is the first barrier between the host and the external environment and is covered by a mucus gel that is… read more here.
Keywords: whereas muc5ac; respiratory epithelium; epithelium; muc5b mainly ... See more keywords
Odor coding in the mammalian olfactory epithelium
Sign Up to like & getrecommendations! Published in 2021 at "Cell and Tissue Research"
DOI: 10.1007/s00441-020-03327-1
Abstract: Noses are extremely sophisticated chemical detectors allowing animals to use scents to interpret and navigate their environments. Odor detection starts with the activation of odorant receptors (ORs), expressed in mature olfactory sensory neurons (OSNs) populating… read more here.
Keywords: odor coding; coding mammalian; olfactory epithelium; mammalian olfactory ... See more keywords
Modulation of olfactory signal detection in the olfactory epithelium: focus on the internal and external environment, and the emerging role of the immune system
Sign Up to like & getrecommendations! Published in 2021 at "Cell and Tissue Research"
DOI: 10.1007/s00441-021-03467-y
Abstract: Detection and discrimination of odorants by the olfactory system plays a pivotal role in animal survival. Olfactory-based behaviors must be adapted to an ever-changing environment. Part of these adaptations includes changes of odorant detection by… read more here.
Keywords: olfactory epithelium; epithelium; system; detection olfactory ... See more keywords
In Vivo Inspection of the Olfactory Epithelium: Feasibility of Robotized Optical Biopsy
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Biomedical Engineering"
DOI: 10.1007/s10439-018-2076-9
Abstract: Inspecting the olfactory cleft can be of high interest, as it is an open access to neurons, and thus an opportunity to collect in situ related data in a non-invasive way. Also, recent studies show… read more here.
Keywords: inspection olfactory; olfactory; vivo inspection; feasibility ... See more keywords
Olfactory cell cultures to investigate health effects of air pollution exposure: Implications for neurodegeneration
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2020.104729
Abstract: Air pollution is a major, global public health concern. A growing body of evidence shows that exposure to air pollutants may impair the brain. Living in highly polluted areas has been linked to several neurodegenerative… read more here.
Keywords: exposure; air; air pollution; olfactory epithelium ... See more keywords
Proinflammatory Cytokines in the Olfactory Mucosa Result in COVID-19 Induced Anosmia
Sign Up to like & getrecommendations! Published in 2020 at "ACS Chemical Neuroscience"
DOI: 10.1021/acschemneuro.0c00249
Abstract: Studies have found increased rates of dysosmia in patients with Novel Coronavirus disease 2019 (COVID-19). However, the mechanism that causes olfactory loss is unknown. The primary objective of this study was to explore local proinflammatory… read more here.
Keywords: olfactory epithelium; covid; proinflammatory cytokines; patients covid ... See more keywords
The Phenomenon of Compensatory Cell Proliferation in Olfactory Epithelium in Fish Caused by Prolonged Exposure to Natural Odorants
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-65854-9
Abstract: It was previously shown that activation of the processes of neurogenesis in the olfactory epithelium (OE) can be caused after intranasal administration of toxic or neurotrophic factors, after axon transection, or as a result of… read more here.
Keywords: olfactory epithelium; natural odorants; cell; exposure ... See more keywords