α‐Synuclein‐Related Mitochondria‐Nrf2 Dysfunction in Parkinson's Disease Olfactory Mucosa
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Neurology"
DOI: 10.1002/ana.27292
Abstract: The objective of this study was to outline the dynamics of the mitochondrial network and cytoprotective response in patients with Parkinson's disease (PD)‐derived olfactory mucosa neurons (ONs) at different disease stages. read more here.
Keywords: disease; related mitochondria; olfactory mucosa; synuclein related ... See more keywords
Endothelin impacts on olfactory processing in rats
Sign Up to like & getrecommendations! Published in 2019 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2018.12.048
Abstract: ABSTRACT In the olfactory epithelium, olfactory sensitive neurons and their axons are surrounded by glia‐like cells called sustentacular cells, which maintain both the structural and ionic integrity of the olfactory mucosa. We have previously found… read more here.
Keywords: olfactory processing; impacts olfactory; gap junctions; endothelin impacts ... See more keywords
HIV-1 detection in the olfactory mucosa of HIV-1-infected participants
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DOI: 10.1097/qad.0000000000002102
Abstract: Objective: HIV infection chronically affects the central nervous system (CNS). Olfactory mucosa is a unique site in the respiratory tract that is directly connected to the CNS; thus we wanted to evaluate olfactory mucosa as… read more here.
Keywords: hiv infected; hiv; olfactory mucosa; mucosa hiv ... See more keywords
The olfactory mucosa, first actor of olfactory detection, is sensitive to glucocorticoid hormone
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Neuroscience"
DOI: 10.1111/ejn.14564
Abstract: The olfactory mucosa (OM) is the primary site of odorant detection, and its axonal projections relay information to brain structures for signal processing. We have previously observed that olfactory function can be affected during a… read more here.
Keywords: olfactory mucosa; detection; olfactory detection; glucocorticoid ... See more keywords
Olfactory mucosa-mesenchymal stem cells with overexpressed Nrf2 modulate angiogenesis and exert anti-inflammation effect in an in vitro traumatic brain injury model
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Medical Research"
DOI: 10.1186/s40001-025-02344-6
Abstract: Traumatic brain injury (TBI) is a major cause of disability and mortality among children and adults in developed countries. Transcription factor nuclear factor erythroid-derived 2-like 2 (Nrf2) has antioxidant, anti-inflammatory and neuroprotective effects and is… read more here.
Keywords: traumatic brain; brain; brain injury; mucosa mesenchymal ... See more keywords
Accurate detection of pathologic α-synuclein in CSF, skin, olfactory mucosa, and urine with a uniform seeding amplification assay
Sign Up to like & getrecommendations! Published in 2025 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-025-02034-8
Abstract: Currently, early diagnosis of dementia with Lewy bodies (DLB) is based on clinical criteria, which is challenging due to overlapping symptoms with other neurodegenerative diseases. Seeding amplification assays, detecting minute amounts of disease causing α-synuclein… read more here.
Keywords: detection; olfactory mucosa; csf; amplification assay ... See more keywords
Prospects for the use of olfactory mucosa cells in bioprinting for the treatment of spinal cord injuries
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DOI: 10.12998/wjcc.v11.i2.322
Abstract: The review focuses on the most important areas of cell therapy for spinal cord injuries. Olfactory mucosa cells are promising for transplantation. Obtaining these cells is safe for patients. The use of olfactory mucosa cells… read more here.
Keywords: cord injuries; mucosa cells; olfactory mucosa; spinal cord ... See more keywords
PMCA-Based Detection of Prions in the Olfactory Mucosa of Patients With Sporadic Creutzfeldt–Jakob Disease
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DOI: 10.3389/fnagi.2022.848991
Abstract: Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare neurodegenerative disorder caused by the conformational conversion of the prion protein (PrPC) into an abnormally folded form, named prion (or PrPSc). The combination of the polymorphism at codon… read more here.
Keywords: creutzfeldt jakob; olfactory mucosa; prpsc; jakob disease ... See more keywords
Oxidative Chemical Stressors Alter the Physiological State of the Nasal Olfactory Mucosa of Atlantic Salmon
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DOI: 10.3390/antiox9111144
Abstract: The olfactory organs of fish have vital functions for chemosensory and defence. Though there have been some ground-breaking discoveries of their involvement in immunity against pathogens in recent years, little is known about how they… read more here.
Keywords: nasal leukocytes; olfactory mucosa; chemical; nasal olfactory ... See more keywords
Development of Good Manufacturing Practice-Compatible Isolation and Culture Methods for Human Olfactory Mucosa-Derived Mesenchymal Stromal Cells
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25020743
Abstract: Demyelination in the central nervous system (CNS) resulting from injury or disease can cause loss of nerve function and paralysis. Cell therapies intended to promote remyelination of axons are a promising avenue of treatment, with… read more here.
Keywords: human olfactory; culture; mesenchymal stromal; stromal cells ... See more keywords