APOLLO-1: a randomized placebo and active-controlled phase III study investigating oliceridine (TRV130), a G protein-biased ligand at the µ-opioid receptor, for management of moderate-to-severe acute pain following bunionectomy
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DOI: 10.2147/jpr.s171013
Abstract: Purpose Oliceridine is a novel G protein-biased µ-opioid receptor agonist designed to provide intravenous (IV) analgesia with a lower risk of opioid-related adverse events (ORAEs) than conventional opioids. Patients and methods APOLLO-1 (NCT02815709) was a… read more here.
Keywords: pain; moderate severe; opioid; oliceridine regimens ... See more keywords