Synthesis of Oligo-(alkyne-triplet)peptide Constructs.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b03231
Abstract: Copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) click synthesis of an Fmoc-(trispropargyl)amino acid building block for solid phase peptide synthesis (SPPS) of oligo-(trialkyne)peptide constructs is reported. These can carry potentially indefinite numbers of inherent alkyne-triplets, which are click… read more here.
Keywords: synthesis; synthesis oligo; peptide constructs; alkyne triplet ... See more keywords