Emerging mitochondrial‐mediated mechanisms involved in oligodendrocyte development
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25151
Abstract: Oligodendrocytes are the myelinating glia of the central nervous system and are generated after oligodendrocyte progenitor cells (OPCs) transition into pre‐oligodendrocytes and then into myelinating oligodendrocytes. Myelin is essential for proper signal transmission within the… read more here.
Keywords: development; oligodendrocyte development; mediated mechanisms; mitochondrial mediated ... See more keywords
Oligodendrocyte-lineage cell exocytosis and L-type prostaglandin D synthase promote oligodendrocyte development and myelination
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.02.14.480339
Abstract: In the developing central nervous system, oligodendrocyte precursor cells (OPCs) differentiate into oligodendrocytes, which form myelin around axons. Oligodendrocytes and myelin are essential for the function of the central nervous system, as evidenced by the… read more here.
Keywords: oligodendrocyte lineage; oligodendrocyte; development; oligodendrocyte development ... See more keywords
MicroRNAs in oligodendrocyte development and remyelination
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.15618
Abstract: Oligodendrocytes are the glial cells responsible for the formation of myelin around axons of the central nervous system (CNS). Myelin is an insulating layer that allows electrical impulses to transmit quickly and efficiently along neurons.… read more here.
Keywords: development remyelination; remyelination; oligodendrocyte development; micrornas oligodendrocyte ... See more keywords
Neuron to Oligodendrocyte Precursor Cell Synapses: Protagonists in Oligodendrocyte Development and Myelination, and Targets for Therapeutics
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2021.779125
Abstract: The development of neuronal circuitry required for cognition, complex motor behaviors, and sensory integration requires myelination. The role of glial cells such as astrocytes and microglia in shaping synapses and circuits have been covered in… read more here.
Keywords: development; oligodendrocyte development; development myelination; cell ... See more keywords
Decreased RNA polymerase III subunit expression leads to defects in oligodendrocyte development
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2023.1167047
Abstract: Introduction RNA polymerase III (Pol III) is a critical enzymatic complex tasked with the transcription of ubiquitous non-coding RNAs including 5S rRNA and all tRNA genes. Despite the constitutive nature of this enzyme, hypomorphic biallelic… read more here.
Keywords: iii; oligodendrocyte development; pol iii; expression ... See more keywords