Factors Associated With Relapse and Treatment of Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease in the United Kingdom
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.42780
Abstract: This cohort study investigates factors associated with long-term risk of relapse among patients with myelin oligodendrocyte glycoprotein antibody–associated disease in the United Kingdom. read more here.
Keywords: associated disease; antibody associated; glycoprotein antibody; factors associated ... See more keywords
Coexistence of Myelin Oligodendrocyte Glycoprotein and Aquaporin-4 Antibodies in Adult and Pediatric Patients.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2019.3656
Abstract: Coexistence of Myelin Oligodendrocyte Glycoprotein and Aquaporin-4 Antibodies in Adult and Pediatric Patients Myelin oligodendrocyte glycoprotein (MOG)–IgG is a biomarker associated with central nervous system–demyelinating disorders termed MOG-IgG–associated disorders. These disorders have overlapping clinical features,… read more here.
Keywords: myelin oligodendrocyte; igg; mog igg; coexistence ... See more keywords
SARS‐COV‐2 a trigger of myelin oligodendrocyte glycoprotein‐associated disorder
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51609
Abstract: SARS‐COV‐2 frequently cause neurological disorders and is sometimes associated with onset of autoimmune diseases affecting the nervous system. Over recent years, a rare but distinct diagnosis designated myelin oligodendrocyte glycoprotein‐associated disorder (MOGAD) has been recognized… read more here.
Keywords: associated disorder; glycoprotein associated; oligodendrocyte glycoprotein; myelin oligodendrocyte ... See more keywords
Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein
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DOI: 10.1002/ana.25291
Abstract: Autoantibodies against myelin oligodendrocyte glycoprotein (MOG) occur in a proportion of patients with inflammatory demyelinating diseases of the central nervous system (CNS). We analyzed their pathogenic activity by affinity‐purifying these antibodies (Abs) from patients and… read more here.
Keywords: myelin oligodendrocyte; antibodies myelin; pathogenicity human; human antibodies ... See more keywords
Clinical Features and Risk of Relapse in Children and Adults with Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease
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DOI: 10.1002/ana.25909
Abstract: The main objective was to compare clinical features, disease course, and myelin oligodendrocyte glycoprotein (MOG) antibody (Ab) dynamics between children and adults with MOG‐Ab–associated disease (MOGAD). read more here.
Keywords: myelin oligodendrocyte; clinical features; associated disease; children adults ... See more keywords
Clinical features of the first attack with leukodystrophy‐like phenotype in children with myelin oligodendrocyte glycoprotein antibody‐associated disorders
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Developmental Neuroscience"
DOI: 10.1002/jdn.10255
Abstract: Myelin oligodendrocyte glycoprotein antibody‐associated disorders (MOGAD) is identified autoimmune disorder with a predominance in paediatric patients, and the disease spectrum has expanded with clinical and radiological patterns. The aim of the study was to describe… read more here.
Keywords: antibody associated; glycoprotein antibody; first attack; associated disorders ... See more keywords
Dose‐dependent effect of myelin oligodendrocyte glycoprotein on visual function and optic nerve damage in experimental autoimmune encephalomyelitis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25007
Abstract: Female Dark Agouti rats were immunized with increasing doses of myelin oligodendrocyte glycoprotein (MOG) to develop experimental autoimmune encephalomyelitis (EAE), a preclinical model of multiple sclerosis. Typical EAE motor impairments were assessed daily and noninvasive… read more here.
Keywords: dose dependent; experimental autoimmune; visual function; autoimmune encephalomyelitis ... See more keywords
Myelin oligodendrocyte glycoprotein-specific antibodies from multiple sclerosis patients exacerbate disease in a humanized mouse model.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2017.09.002
Abstract: Myelin oligodendrocyte glycoprotein (MOG) is exposed on the outer surface of the myelin sheath, and as such, represents a possible target antigen for antibodies in multiple sclerosis (MS) and other demyelinating diseases. However, despite extensive… read more here.
Keywords: myelin oligodendrocyte; mog; specific antibodies; oligodendrocyte glycoprotein ... See more keywords
Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies in patients with optic neuritis and seizures
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2018.01.042
Abstract: We describe four patients who experienced optic neuritis (ON) and seizures and were found to have antibodies to myelin oligodendrocyte glycoprotein (MOG) in serum. The index case was a previously healthy 39-year-old man who developed… read more here.
Keywords: myelin oligodendrocyte; neuritis seizures; optic neuritis; oligodendrocyte glycoprotein ... See more keywords
The prevalence and prognostic value of myelin oligodendrocyte glycoprotein antibody in adult optic neuritis
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DOI: 10.1016/j.jns.2018.11.029
Abstract: BACKGROUND AND OBJECTIVE Adult demyelinating optic neuritis (ON) with positive myelin-oligodendrocyte glycoprotein antibody (MOG-Ab) has distinct clinical features. This study aimed to investigate the point prevalence, relationship with steroid dependency and prognosis value of MOG-Ab… read more here.
Keywords: adult; myelin oligodendrocyte; antibody; optic neuritis ... See more keywords
Clinical characteristics of myelin oligodendrocyte glycoprotein antibody neuromyelitis optica spectrum disorder.
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DOI: 10.1016/j.msard.2019.02.023
Abstract: BACKGROUND Serological antibodies against myelin oligodendrocyte glycoprotein (MOG) are associated with a relapsing autoimmune demyelinating disease of the central nervous system. Initially identified in the context of acute disseminated encephalomyelitis, persistent seropositivity of MOG antibodies… read more here.
Keywords: myelin oligodendrocyte; antibody; spectrum disorder; neuromyelitis optica ... See more keywords