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   Articles with "oligodendrocyte glycoprotein" as a keyword



Factors Associated With Relapse and Treatment of Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease in the United Kingdom

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2021.42780

Abstract: This cohort study investigates factors associated with long-term risk of relapse among patients with myelin oligodendrocyte glycoprotein antibody–associated disease in the United Kingdom. read more here.

Keywords: associated disease; antibody associated; glycoprotein antibody; factors associated ... See more keywords

Coexistence of Myelin Oligodendrocyte Glycoprotein and Aquaporin-4 Antibodies in Adult and Pediatric Patients.

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recommendations! Published in 2019 at "JAMA neurology"

DOI: 10.1001/jamaneurol.2019.3656

Abstract: Coexistence of Myelin Oligodendrocyte Glycoprotein and Aquaporin-4 Antibodies in Adult and Pediatric Patients Myelin oligodendrocyte glycoprotein (MOG)–IgG is a biomarker associated with central nervous system–demyelinating disorders termed MOG-IgG–associated disorders. These disorders have overlapping clinical features,… read more here.

Keywords: myelin oligodendrocyte; igg; mog igg; coexistence ... See more keywords

SARS‐COV‐2 a trigger of myelin oligodendrocyte glycoprotein‐associated disorder

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recommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.51609

Abstract: SARS‐COV‐2 frequently cause neurological disorders and is sometimes associated with onset of autoimmune diseases affecting the nervous system. Over recent years, a rare but distinct diagnosis designated myelin oligodendrocyte glycoprotein‐associated disorder (MOGAD) has been recognized… read more here.

Keywords: associated disorder; glycoprotein associated; oligodendrocyte glycoprotein; myelin oligodendrocyte ... See more keywords
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Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein

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recommendations! Published in 2018 at "Annals of Neurology"

DOI: 10.1002/ana.25291

Abstract: Autoantibodies against myelin oligodendrocyte glycoprotein (MOG) occur in a proportion of patients with inflammatory demyelinating diseases of the central nervous system (CNS). We analyzed their pathogenic activity by affinity‐purifying these antibodies (Abs) from patients and… read more here.

Keywords: myelin oligodendrocyte; antibodies myelin; pathogenicity human; human antibodies ... See more keywords

Clinical Features and Risk of Relapse in Children and Adults with Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease

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recommendations! Published in 2020 at "Annals of Neurology"

DOI: 10.1002/ana.25909

Abstract: The main objective was to compare clinical features, disease course, and myelin oligodendrocyte glycoprotein (MOG) antibody (Ab) dynamics between children and adults with MOG‐Ab–associated disease (MOGAD). read more here.

Keywords: myelin oligodendrocyte; clinical features; associated disease; children adults ... See more keywords

Cognitive Outcomes in Myelin Oligodendrocyte Glycoprotein‐IgG Associated Disease Compared to Multiple Sclerosis

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recommendations! Published in 2025 at "Brain and Behavior"

DOI: 10.1002/brb3.70310

Abstract: Little is known about cognitive outcomes in people with myelin oligodendrocyte glycoprotein‐IgG associated disease (pwMOGAD). While there are similarities between MOGAD and multiple sclerosis (MS), further evaluation is needed to establish the distinct cognitive trajectories… read more here.

Keywords: cognitive outcomes; glycoprotein igg; oligodendrocyte glycoprotein; associated disease ... See more keywords

Clinical features of the first attack with leukodystrophy‐like phenotype in children with myelin oligodendrocyte glycoprotein antibody‐associated disorders

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recommendations! Published in 2023 at "International Journal of Developmental Neuroscience"

DOI: 10.1002/jdn.10255

Abstract: Myelin oligodendrocyte glycoprotein antibody‐associated disorders (MOGAD) is identified autoimmune disorder with a predominance in paediatric patients, and the disease spectrum has expanded with clinical and radiological patterns. The aim of the study was to describe… read more here.

Keywords: antibody associated; glycoprotein antibody; first attack; associated disorders ... See more keywords

Dose‐dependent effect of myelin oligodendrocyte glycoprotein on visual function and optic nerve damage in experimental autoimmune encephalomyelitis

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recommendations! Published in 2022 at "Journal of Neuroscience Research"

DOI: 10.1002/jnr.25007

Abstract: Female Dark Agouti rats were immunized with increasing doses of myelin oligodendrocyte glycoprotein (MOG) to develop experimental autoimmune encephalomyelitis (EAE), a preclinical model of multiple sclerosis. Typical EAE motor impairments were assessed daily and noninvasive… read more here.

Keywords: dose dependent; experimental autoimmune; visual function; autoimmune encephalomyelitis ... See more keywords

Myelin oligodendrocyte glycoprotein-specific antibodies from multiple sclerosis patients exacerbate disease in a humanized mouse model.

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recommendations! Published in 2018 at "Journal of autoimmunity"

DOI: 10.1016/j.jaut.2017.09.002

Abstract: Myelin oligodendrocyte glycoprotein (MOG) is exposed on the outer surface of the myelin sheath, and as such, represents a possible target antigen for antibodies in multiple sclerosis (MS) and other demyelinating diseases. However, despite extensive… read more here.

Keywords: myelin oligodendrocyte; mog; specific antibodies; oligodendrocyte glycoprotein ... See more keywords

Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies in patients with optic neuritis and seizures

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recommendations! Published in 2018 at "Journal of the Neurological Sciences"

DOI: 10.1016/j.jns.2018.01.042

Abstract: We describe four patients who experienced optic neuritis (ON) and seizures and were found to have antibodies to myelin oligodendrocyte glycoprotein (MOG) in serum. The index case was a previously healthy 39-year-old man who developed… read more here.

Keywords: myelin oligodendrocyte; neuritis seizures; optic neuritis; oligodendrocyte glycoprotein ... See more keywords

The prevalence and prognostic value of myelin oligodendrocyte glycoprotein antibody in adult optic neuritis

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recommendations! Published in 2019 at "Journal of the Neurological Sciences"

DOI: 10.1016/j.jns.2018.11.029

Abstract: BACKGROUND AND OBJECTIVE Adult demyelinating optic neuritis (ON) with positive myelin-oligodendrocyte glycoprotein antibody (MOG-Ab) has distinct clinical features. This study aimed to investigate the point prevalence, relationship with steroid dependency and prognosis value of MOG-Ab… read more here.

Keywords: adult; myelin oligodendrocyte; antibody; optic neuritis ... See more keywords